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    Prevalence of schizophrenia in China between 1990 and 2010

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    Author
    Chan, KY; Zhao, F-F; Meng, S; Demaio, AR; Reed, C; Theodoratou, E; Campbell, H; Wang, W; Rudan, I
    Date
    2015-06-01
    Source Title
    Journal of Global Health
    Publisher
    UNIV EDINBURGH, GLOBAL HEALTH SOC
    University of Melbourne Author/s
    Chan, Kit Yee
    Affiliation
    Melbourne School of Population and Global Health
    Metadata
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    Document Type
    Journal Article
    Citations
    Chan, K. Y., Zhao, F. -F., Meng, S., Demaio, A. R., Reed, C., Theodoratou, E., Campbell, H., Wang, W. & Rudan, I. (2015). Prevalence of schizophrenia in China between 1990 and 2010. JOURNAL OF GLOBAL HEALTH, 5 (1), pp.142-149. https://doi.org/10.7189/jogh.05.010410.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/260083
    DOI
    10.7189/jogh.05.010410
    Abstract
    BACKGROUND: Dramatic development and changes in lifestyle in many low and middle-income countries (LMIC) over the past three decades may have affected mental health of their populations. Being the largest country and having the most striking record of development, industrialization and urbanization, China provides an important opportunity for studying the nature and magnitude of possible effects. METHODS: We reviewed CNKI, WanFang and PubMed databases for epidemiological studies of schizophrenia in mainland China published between 1990 and 2010. We identified 42 studies that reported schizophrenia prevalence using internationally recognized diagnostic criteria, with breakdown by rural and urban residency. The analysis involved a total of 2 284 957 persons, with 10 506 diagnosed with schizophrenia. Bayesian methods were used to estimate the probability of case of schizophrenia ("prevalence") by type of residency in different years. FINDINGS: In urban China, lifetime prevalence was 0.39% (0.37-0.41%) in 1990, 0.57% (0.55-0.59%) in 2000 and 0.83% (0.75-0.91%) in 2010. In rural areas, the corresponding rates were 0.37% (0.34-0.40%), 0.43% (0.42-0.44%) and 0.50% (0.47-0.53%). In 1990 there were 3.09 (2.87-3.32) million people in China affected with schizophrenia during their lifetime. The number of cases rose to 7.16 (6.57-7.75) million in 2010, a 132% increase, while the total population increased by 18%. The contribution of cases from urban areas to the overall burden increased from 27% in 1990 to 62% in 2010. CONCLUSIONS: The prevalence of schizophrenia in China has more than doubled between 1990 and 2010, with rates being particularly high in the most developed areas of modern China. This has broad implications, as the ongoing development in LMIC countries may be increasing the global prevalence of schizophrenia.

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