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dc.contributor.authorKhan, F
dc.contributor.authorAmatya, B
dc.contributor.authorTurner-Stokes, L
dc.date.accessioned2021-02-05T00:41:16Z
dc.date.available2021-02-05T00:41:16Z
dc.date.issued2011
dc.identifier.citationKhan, F., Amatya, B. & Turner-Stokes, L. (2011). Symptomatic therapy and rehabilitation in primary progressive multiple sclerosis.. Neurol Res Int, 2011, pp.740505-. https://doi.org/10.1155/2011/740505.
dc.identifier.issn2090-1852
dc.identifier.urihttp://hdl.handle.net/11343/260109
dc.description.abstractMultiple sclerosis (MS) is an autoimmune inflammatory demyelinating disease of the central nervous system and a major cause of chronic neurological disability in young adults. Primary progressive MS (PPMS) constitutes about 10% of cases, and is characterized by a steady decline in function with no acute attacks. The rate of deterioration from disease onset is more rapid than relapsing remitting and secondary progressive MS types. Multiple system involvement at onset and rapid early progression have a worse prognosis. PPMS can cause significant disability and impact on quality of life. Recent studies are biased in favour of relapsing remitting patients as treatment is now available for them and they are more likely to be seen at MS clinics. Since prognosis for PPMS is worse than other types of MS, the focus of rehabilitation is on managing disability and enhancing participation, and application of a "neuropalliative" approach as the disease progresses. This chapter presents the symptomatic treatment and rehabilitation for persons with MS, including PPMS. A multidisciplinary approach optimizes the intermediate and long-term medical, psychological and social outcomes in this population. Restoration and maintenance of functional independence and societal reintegration, and issues relating to quality of life are addressed in rehabilitation processes.
dc.languageeng
dc.publisherHindawi Limited
dc.titleSymptomatic therapy and rehabilitation in primary progressive multiple sclerosis.
dc.typeJournal Article
dc.identifier.doi10.1155/2011/740505
melbourne.affiliation.departmentMedicine and Radiology
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleNeurology Research International
melbourne.source.volume2011
melbourne.source.pages740505-
dc.rights.licenseCC BY
melbourne.elementsid965057
melbourne.openaccess.pmchttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196037
melbourne.contributor.authorKhan, Farees
melbourne.contributor.authorAmatya, Bhasker
melbourne.contributor.authorBhasker, Amatya
dc.identifier.eissn2090-1860
melbourne.accessrightsOpen Access


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