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dc.contributor.authorTye-Din, JA
dc.contributor.authorCameron, DJS
dc.contributor.authorDaveson, AJ
dc.contributor.authorDay, AS
dc.contributor.authorDellsperger, P
dc.contributor.authorHogan, C
dc.contributor.authorNewnham, ED
dc.contributor.authorShepherd, SJ
dc.contributor.authorSteele, RH
dc.contributor.authorWienholt, L
dc.contributor.authorVarney, MD
dc.date.accessioned2021-02-05T00:42:47Z
dc.date.available2021-02-05T00:42:47Z
dc.date.issued2015-04-01
dc.identifier.citationTye-Din, J. A., Cameron, D. J. S., Daveson, A. J., Day, A. S., Dellsperger, P., Hogan, C., Newnham, E. D., Shepherd, S. J., Steele, R. H., Wienholt, L. & Varney, M. D. (2015). Appropriate clinical use of human leukocyte antigen typing for coeliac disease: an Australasian perspective. INTERNAL MEDICINE JOURNAL, 45 (4), pp.441-450. https://doi.org/10.1111/imj.12716.
dc.identifier.issn1444-0903
dc.identifier.urihttp://hdl.handle.net/11343/260120
dc.description.abstractThe past decade has seen human leukocyte antigen (HLA) typing emerge as a remarkably popular test for the diagnostic work-up of coeliac disease with high patient acceptance. Although limited in its positive predictive value for coeliac disease, the strong disease association with specific HLA genes imparts exceptional negative predictive value to HLA typing, enabling a negative result to exclude coeliac disease confidently. In response to mounting evidence that the clinical use and interpretation of HLA typing often deviates from best practice, this article outlines an evidence-based approach to guide clinically appropriate use of HLA typing, and establishes a reporting template for pathology providers to improve communication of results.
dc.languageEnglish
dc.publisherWILEY
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0
dc.titleAppropriate clinical use of human leukocyte antigen typing for coeliac disease: an Australasian perspective
dc.typeJournal Article
dc.identifier.doi10.1111/imj.12716
melbourne.affiliation.departmentGeneral Practice
melbourne.affiliation.departmentMedical Biology (W.E.H.I.)
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleInternal Medicine Journal
melbourne.source.volume45
melbourne.source.issue4
melbourne.source.pages441-450
dc.rights.licenseCC BY-NC
melbourne.elementsid967639
melbourne.contributor.authorHogan, Christopher
melbourne.contributor.authorTye-Din, Jason
dc.identifier.eissn1445-5994
melbourne.accessrightsOpen Access


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