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dc.contributor.authorCowley, MJ
dc.contributor.authorPinese, M
dc.contributor.authorKassahn, KS
dc.contributor.authorWaddell, N
dc.contributor.authorPearson, JV
dc.contributor.authorGrimmond, SM
dc.contributor.authorBiankin, AV
dc.contributor.authorHautaniemi, S
dc.contributor.authorWu, J
dc.date.accessioned2021-02-05T00:44:41Z
dc.date.available2021-02-05T00:44:41Z
dc.date.issued2012-01-01
dc.identifierpii: gkr967
dc.identifier.citationCowley, M. J., Pinese, M., Kassahn, K. S., Waddell, N., Pearson, J. V., Grimmond, S. M., Biankin, A. V., Hautaniemi, S. & Wu, J. (2012). PINA v2.0: mining interactome modules. NUCLEIC ACIDS RESEARCH, 40 (D1), pp.D862-D865. https://doi.org/10.1093/nar/gkr967.
dc.identifier.issn0305-1048
dc.identifier.urihttp://hdl.handle.net/11343/260132
dc.description.abstractThe Protein Interaction Network Analysis (PINA) platform is a comprehensive web resource, which includes a database of unified protein-protein interaction data integrated from six manually curated public databases, and a set of built-in tools for network construction, filtering, analysis and visualization. The second version of PINA enhances its utility for studies of protein interactions at a network level, by including multiple collections of interaction modules identified by different clustering approaches from the whole network of protein interactions ('interactome') for six model organisms. All identified modules are fully annotated by enriched Gene Ontology terms, KEGG pathways, Pfam domains and the chemical and genetic perturbations collection from MSigDB. Moreover, a new tool is provided for module enrichment analysis in addition to simple query function. The interactome data are also available on the web site for further bioinformatics analysis. PINA is freely accessible at http://cbg.garvan.unsw.edu.au/pina/.
dc.languageEnglish
dc.publisherOXFORD UNIV PRESS
dc.titlePINA v2.0: mining interactome modules
dc.typeJournal Article
dc.identifier.doi10.1093/nar/gkr967
melbourne.affiliation.departmentCentre for Cancer Research
melbourne.affiliation.facultyCollected Works
melbourne.source.titleNucleic Acids Research
melbourne.source.volume40
melbourne.source.issueD1
melbourne.source.pagesD862-D865
dc.rights.licenseCC BY-NC
melbourne.elementsid1033278
melbourne.contributor.authorGrimmond, Sean
dc.identifier.eissn1362-4962
melbourne.accessrightsOpen Access


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