Generating kidney tissue from pluripotent stem cells

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Author
Little, MHDate
2016-01-01Source Title
Cell Death DiscoveryPublisher
NATURE PUBLISHING GROUPUniversity of Melbourne Author/s
Little, MelissaAffiliation
Paediatrics (RCH)Metadata
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Journal ArticleCitations
Little, M. H. (2016). Generating kidney tissue from pluripotent stem cells. CELL DEATH DISCOVERY, 2 (1), https://doi.org/10.1038/cddiscovery.2016.53.Access Status
Open AccessAbstract
With the isolation of human pluripotent stem cells came the possibility of generating specific cell types for regenerative medicine. This has required the development of protocols for directed differentiation into many distinct cell types. One of the more complicated tissue types to recreate is the kidney. Here we review recent progress towards the recreation of not only specific kidney cell types but complex kidney organoids, models of the developing human organ, in vitro. We will also discuss potential short and long term applications of these approaches.
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