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    Generating kidney tissue from pluripotent stem cells

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    9
    Author
    Little, MH
    Date
    2016-01-01
    Source Title
    Cell Death Discovery
    Publisher
    NATURE PUBLISHING GROUP
    University of Melbourne Author/s
    Little, Melissa
    Affiliation
    Paediatrics (RCH)
    Metadata
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    Document Type
    Journal Article
    Citations
    Little, M. H. (2016). Generating kidney tissue from pluripotent stem cells. CELL DEATH DISCOVERY, 2 (1), https://doi.org/10.1038/cddiscovery.2016.53.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/260169
    DOI
    10.1038/cddiscovery.2016.53
    Abstract
    With the isolation of human pluripotent stem cells came the possibility of generating specific cell types for regenerative medicine. This has required the development of protocols for directed differentiation into many distinct cell types. One of the more complicated tissue types to recreate is the kidney. Here we review recent progress towards the recreation of not only specific kidney cell types but complex kidney organoids, models of the developing human organ, in vitro. We will also discuss potential short and long term applications of these approaches.

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