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dc.contributor.authorMuller, S
dc.contributor.authorParsons, MS
dc.contributor.authorKohler, H
dc.contributor.authorGrant, M
dc.date.accessioned2021-02-05T01:03:31Z
dc.date.available2021-02-05T01:03:31Z
dc.date.issued2016-02-05
dc.identifier.citationMuller, S., Parsons, M. S., Kohler, H. & Grant, M. (2016). The Significance of a Common idiotype (1F7) on Antibodies against Human immune Deficiency virus Type 1 and Hepatitis C virus. FRONTIERS IN ONCOLOGY, 6 (FEB), https://doi.org/10.3389/fonc.2016.00011.
dc.identifier.issn2234-943X
dc.identifier.urihttp://hdl.handle.net/11343/260255
dc.description.abstractIn this review, we trace the concept and potential functional role of regulatory idiotypes in the immune response to human immunodeficiency virus type 1 (HIV-1), simian immunodeficiency virus, and hepatitis C virus (HCV). A major idiotype involved in these viral infections is recognized and defined by a murine monoclonal antibody (1F7). Antibodies expressing the idiotype defined by 1F7 are dominant in HIV-1 infection and are also found on many broadly neutralizing antibodies against HIV-1. This regulatory idiotypic axis offers opportunities for exploitation in vaccine development for HIV-1, HCV, and other chronic viral infections.
dc.languageEnglish
dc.publisherFRONTIERS MEDIA SA
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleThe Significance of a Common idiotype (1F7) on Antibodies against Human immune Deficiency virus Type 1 and Hepatitis C virus
dc.typeJournal Article
dc.identifier.doi10.3389/fonc.2016.00011
melbourne.affiliation.departmentMicrobiology and Immunology
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleFrontiers in Oncology
melbourne.source.volume6
melbourne.source.issueFEB
dc.rights.licenseCC BY
melbourne.elementsid1042295
melbourne.contributor.authorParsons, Matt
dc.identifier.eissn2234-943X
melbourne.accessrightsOpen Access


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