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dc.contributor.authorParry, SM
dc.contributor.authorPuthucheary, ZA
dc.date.accessioned2021-02-05T01:15:42Z
dc.date.available2021-02-05T01:15:42Z
dc.date.issued2015-01-01
dc.identifierpii: 36
dc.identifier.citationParry, S. M. & Puthucheary, Z. A. (2015). The impact of extended bed rest on the musculoskeletal system in the critical care environment. EXTREME PHYSIOLOGY & MEDICINE, 4 (1), https://doi.org/10.1186/s13728-015-0036-7.
dc.identifier.issn2046-7648
dc.identifier.urihttp://hdl.handle.net/11343/260329
dc.description.abstractProlonged immobility is harmful with rapid reductions in muscle mass, bone mineral density and impairment in other body systems evident within the first week of bed rest which is further exacerbated in individuals with critical illness. Our understanding of the aetiology and secondary consequences of prolonged immobilization in the critically ill is improving with recent and ongoing research to establish the cause, effect, and best treatment options. This review aims to describe the current literature on bed rest models for examining immobilization-induced changes in the musculoskeletal system and pathophysiology of immobilisation in critical illness including examination of intracellular signalling processes involved. Finally, the review examines the current barriers to early activity and mobilization and potential rehabilitation strategies, which are being, investigated which may reverse the effects of prolonged bed rest. Addressing the deleterious effects of immobilization is a major step in treatment and prevention of the public health issue, that is, critical illness survivorship.
dc.languageEnglish
dc.publisherBMC
dc.titleThe impact of extended bed rest on the musculoskeletal system in the critical care environment
dc.typeJournal Article
dc.identifier.doi10.1186/s13728-015-0036-7
melbourne.affiliation.departmentMedicine Dentistry & Health Sciences
melbourne.affiliation.facultyCollected Works
melbourne.source.titleExtreme physiology & medicine
melbourne.source.volume4
melbourne.source.issue1
dc.rights.licenseCC BY
melbourne.elementsid1051367
melbourne.contributor.authorParry, Selina
dc.identifier.eissn2046-7648
melbourne.accessrightsOpen Access


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