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dc.contributor.authorMcGuire, LI
dc.contributor.authorPoleggi, A
dc.contributor.authorPoggiolini, I
dc.contributor.authorSuardi, S
dc.contributor.authorGrznarova, K
dc.contributor.authorShi, S
dc.contributor.authorde Vil, B
dc.contributor.authorSarros, S
dc.contributor.authorSatoh, K
dc.contributor.authorCheng, K
dc.contributor.authorCramm, M
dc.contributor.authorFairfoul, G
dc.contributor.authorSchmitz, M
dc.contributor.authorZerr, I
dc.contributor.authorCras, P
dc.contributor.authorEquestre, M
dc.contributor.authorTagliavini, F
dc.contributor.authorAtarashi, R
dc.contributor.authorKnox, D
dc.contributor.authorCollins, S
dc.contributor.authorHaik, S
dc.contributor.authorParchi, P
dc.contributor.authorPocchiari, M
dc.contributor.authorGreen, A
dc.date.accessioned2021-02-05T01:23:23Z
dc.date.available2021-02-05T01:23:23Z
dc.date.issued2016-07-01
dc.identifier.citationMcGuire, L. I., Poleggi, A., Poggiolini, I., Suardi, S., Grznarova, K., Shi, S., de Vil, B., Sarros, S., Satoh, K., Cheng, K., Cramm, M., Fairfoul, G., Schmitz, M., Zerr, I., Cras, P., Equestre, M., Tagliavini, F., Atarashi, R., Knox, D. ,... Green, A. (2016). Cerebrospinal Fluid Real-Time Quaking-Induced Conversion Is a Robust and Reliable Test for Sporadic Creutzfeldt-Jakob Disease: An International Study. ANNALS OF NEUROLOGY, 80 (1), pp.160-165. https://doi.org/10.1002/ana.24679.
dc.identifier.issn0364-5134
dc.identifier.urihttp://hdl.handle.net/11343/260379
dc.description.abstractReal-time quaking-induced conversion (RT-QuIC) has been proposed as a sensitive diagnostic test for sporadic Creutzfeldt-Jakob disease; however, before this assay can be introduced into clinical practice, its reliability and reproducibility need to be demonstrated. Two international ring trials were undertaken in which a set of 25 cerebrospinal fluid samples were analyzed by a total of 11 different centers using a range of recombinant prion protein substrates and instrumentation. The results show almost complete concordance between the centers and demonstrate that RT-QuIC is a suitably reliable and robust technique for clinical practice. Ann Neurol 2016;80:160-165.
dc.languageEnglish
dc.publisherWILEY-BLACKWELL
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleCerebrospinal Fluid Real-Time Quaking-Induced Conversion Is a Robust and Reliable Test for Sporadic Creutzfeldt-Jakob Disease: An International Study
dc.typeJournal Article
dc.identifier.doi10.1002/ana.24679
melbourne.affiliation.departmentFlorey Department of Neuroscience and Mental Health
melbourne.affiliation.departmentMedicine (RMH)
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleAnnals of Neurology
melbourne.source.volume80
melbourne.source.issue1
melbourne.source.pages160-165
dc.rights.licenseCC BY
melbourne.elementsid1057712
melbourne.contributor.authorCollins, Steven
melbourne.contributor.authorSarros, Shannon
dc.identifier.eissn1531-8249
melbourne.accessrightsOpen Access


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