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dc.contributor.authorAshman, RB
dc.contributor.authorVijayan, D
dc.contributor.authorWells, CA
dc.date.accessioned2021-02-05T01:38:15Z
dc.date.available2021-02-05T01:38:15Z
dc.date.issued2011-01-01
dc.identifier.citationAshman, R. B., Vijayan, D. & Wells, C. A. (2011). IL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection. CLINICAL & DEVELOPMENTAL IMMUNOLOGY, 2011, https://doi.org/10.1155/2011/686597.
dc.identifier.issn1740-2522
dc.identifier.urihttp://hdl.handle.net/11343/260475
dc.description.abstractIL-12 is a cytokine with links to both innate and adaptive immunity systems. In mice, its deletion leads to acute susceptibility to oral infection with the yeast Candida albicans, whereas such mice are resistant to systemic disease. However, it is an essential component of the adaptive response that leads to the generation of Th1-type cytokine responses and protection against disseminated disease. This paper presents an overview of the role of IL-12 in models of systemic and mucosal infection and the possible relationships between them.
dc.languageEnglish
dc.publisherHINDAWI LTD
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleIL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection
dc.typeJournal Article
dc.identifier.doi10.1155/2011/686597
melbourne.affiliation.departmentAnatomy and Neuroscience
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleClinical and Developmental Immunology
melbourne.source.volume2011
dc.rights.licenseCC BY
melbourne.elementsid1062923
melbourne.contributor.authorWells, Christine
dc.identifier.eissn1740-2530
melbourne.accessrightsOpen Access


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