Show simple item record

dc.contributor.authorSarris, J
dc.contributor.authorPerkins, D
dc.contributor.authorCribb, L
dc.contributor.authorSchubert, V
dc.contributor.authorOpaleye, E
dc.contributor.authorBouso, JC
dc.contributor.authorScheidegger, M
dc.contributor.authorAicher, H
dc.contributor.authorSimonova, H
dc.contributor.authorHorák, M
dc.contributor.authorGalvão-Coelho, NL
dc.contributor.authorCastle, D
dc.contributor.authorTófoli, LF
dc.date.accessioned2021-02-07T01:06:15Z
dc.date.available2021-02-07T01:06:15Z
dc.date.issued2021-04
dc.identifier.citationSarris, J., Perkins, D., Cribb, L., Schubert, V., Opaleye, E., Bouso, J. C., Scheidegger, M., Aicher, H., Simonova, H., Horák, M., Galvão-Coelho, N. L., Castle, D. & Tófoli, L. F. (2021). Ayahuasca use and reported effects on depression and anxiety symptoms: An international cross-sectional study of 11,912 consumers. Journal of Affective Disorders Reports, 4, pp.100098-100098. https://doi.org/10.1016/j.jadr.2021.100098.
dc.identifier.issn2666-9153
dc.identifier.urihttp://hdl.handle.net/11343/260495
dc.description.abstractBackground Ayahuasca is a psychoactive Amazonian brew which has emerging data indicating that it has antidepressant and anxiolytic properties. Methods This paper uses data from the Global Ayahuasca Project (GAP), which was undertaken across 2017-2020 and involved 11912 people, to examine the perceived effects of ayahuasca consumption on affective symptoms. The study focused on the subsample reporting depression or anxiety diagnoses at time of Ayahuasca consumption (n = 2011). Results Of participants reporting depression (n=1571) or anxiety (n=1125) at the time of consuming Ayahuasca, 78% reported that their depression was either ‘very much’ improved (46%), or ‘completely resolved’ (32%); while 70% of those with anxiety reported that their symptoms were ‘very much’ improved (54%), or ‘completely resolved’ (16%). A range of factors were associated with greater reported affective symptoms improvement, including subjective mystical experience, number of Ayahuasca sessions, and number of personal psychological insights experienced. 2.7% and 4.5% of drinkers with depression or anxiety, respectively, reported worsening of symptoms. Limitations This study is recognized as a cross-sectional analysis which cannot assess treatment efficacy. Selection bias may exist due to survey-respondents with favorable experience being potentially biased towards participation. Conclusions Drinkers of Ayahuasca in naturalistic settings perceived remarkable benefits for their affective symptoms in this survey assessment. There is no obvious evidence of negative mental health effects being associated with long-term consumption. Additional randomized controlled trial evidence is required to establish the efficacy of Ayahuasca in affective disorders, and to understand the worsened symptoms reported by a small percentage of drinkers.
dc.languageen
dc.publisherElsevier BV
dc.titleAyahuasca use and reported effects on depression and anxiety symptoms: An international cross-sectional study of 11,912 consumers
dc.typeJournal Article
dc.identifier.doi10.1016/j.jadr.2021.100098
melbourne.affiliation.departmentSchool of Social and Political Sciences
melbourne.source.titleJournal of Affective Disorders
melbourne.source.volume4
melbourne.source.pages100098-100098
melbourne.identifier.nhmrc1125000
dc.rights.licensePublisher's own licence
melbourne.elementsid1493575
melbourne.contributor.authorSchubert, Vijoleta
melbourne.contributor.authorPerkins, Daniel
melbourne.identifier.fundernameidNHMRC, 1125000
melbourne.accessrightsOpen Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record