Molecular epidemiology of adenovirus isolates from patients diagnosed with intussusception in Melbourne, Australia
AuthorSelvaraj, G; Kirkwood, C; Bines, J; Buttery, J
Source TitleJOURNAL OF CLINICAL MICROBIOLOGY
PublisherAMER SOC MICROBIOLOGY
AffiliationPaediatrics Royal Children'S Hospital
Document TypeJournal Article
CitationsSelvaraj, G., Kirkwood, C., Bines, J. & Buttery, J. (2006). Molecular epidemiology of adenovirus isolates from patients diagnosed with intussusception in Melbourne, Australia. JOURNAL OF CLINICAL MICROBIOLOGY, 44 (9), pp.3371-3373. https://doi.org/10.1128/JCM.01289-06.
Access StatusAccess this item via the Open Access location
Open Access at PMChttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1594688
C1 - Journal Articles Refereed
Twenty-one intussusception (IS)-associated and 59 temporally linked adenoviral isolates from clinical infections were compared. Species C (15/21 IS- and 32/59 non-IS-associated isolates) dominated. Of these, serotype 2 (AdV-2) (7/15 IS-associated isolates) and serotype 1 (AdV-1) (16/32 non-IS-associated isolates) were the most commonly identified serotypes. DNA restriction analysis of AdV-2 isolates identified six genomic types; of these, type D2 (3/7 IS- and 8/11 non-IS-associated isolates) was the dominant type after BamHI and SmaI digestion. IS-associated isolates are similar to circulating non-IS-associated strains.
KeywordsPaediatrics; Epidemiology ; Child Health; Digestive System Disorders
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