Azithromycin failure in Mycoplasma genitalium urethritis

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    Author
    Bradshaw, CS; Jensen, JS; Tabrizi, SN; Read, TRH; Garland, SM; Hopkins, CA; Moss, LM; Fairley, CK
    Date
    2006-07-01
    Source Title
    Emerging Infectious Diseases
    Publisher
    CENTER DISEASE CONTROL
    University of Melbourne Author/s
    BRADSHAW, CATRIONA SUSAN; Tabrizi, Sepehr; Wark, Suzanne; Fairley, Christopher
    Affiliation
    Population Health
    Metadata
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    Document Type
    Journal Article
    Citations
    Bradshaw, C. S., Jensen, J. S., Tabrizi, S. N., Read, T. R. H., Garland, S. M., Hopkins, C. A., Moss, L. M. & Fairley, C. K. (2006). Azithromycin failure in Mycoplasma genitalium urethritis. EMERGING INFECTIOUS DISEASES, 12 (7), pp.1149-1152. https://doi.org/10.3201/eid1207.051558.
    Access Status
    Access this item via the Open Access location
    URI
    http://hdl.handle.net/11343/26331
    DOI
    10.3201/eid1207.051558
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291056
    Description

    C1 - Journal Articles Refereed
    Abstract
    We report significant failure rates (28%, 95% confidence interval 15%-45%) after administering 1 g azithromycin to men with Mycoplasma genitalium-positive nongonococcal urethritis. In vitro evidence supported reduced susceptibility of M. genitalium to macrolides. Moxifloxacin administration resulted in rapid symptom resolution and eradication of infection in all cases. These findings have implications for management of urethritis.
    Keywords
    Preventive Medicine; Preventive Medicine

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