Mitochondrial genomes of parasitic nematodes - progress and perspectives
AuthorHu, M; Gasser, RB
Source TitleTrends in Parasitology
PublisherELSEVIER SCI LTD
Document TypeJournal Article
CitationsHu, M. & Gasser, R. B. (2006). Mitochondrial genomes of parasitic nematodes - progress and perspectives. TRENDS IN PARASITOLOGY, 22 (2), pp.78-84. https://doi.org/10.1016/j.pt.2005.12.003.
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C1 - Journal Articles Refereed
Mitochondria are subcellular organelles in which oxidative phosphorylation and other important biochemical functions take place within the cell. Within these organelles is a mitochondrial (mt) genome, which is distinct from, but cooperates with, the nuclear genome of the cell. Studying mt genomes has implications for various fundamental areas, including mt biochemistry, physiology and molecular biology. Importantly, the mt genome is a rich source of markers for population genetic and systematic studies. To date, more than 696 mt genomes have been sequenced for a range of metazoan organisms. However, few of these are from parasitic nematodes, despite their socioeconomic importance and the need for fundamental investigations into areas such as nematode genetics, systematics and ecology. In this article, we review knowledge and recent progress in mt genomics of parasitic nematodes, summarize applications of mt gene markers to the study of population genetics, systematics, epidemiology and evolution of key nematodes, and highlight some prospects and opportunities for future research.
KeywordsParasitology ; Biological Sciences
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