A pilot randomized, double-blind, placebo-controlled study of granisetron in the treatment of sexual dysfunction in women associated with antidepressant use
Author
Jespersen, S; Berk, M; Van Wyk, C; Dean, O; Dodd, S; Szabo, CP; Maud, CDate
2004-05-01Source Title
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGYPublisher
LIPPINCOTT WILLIAMS & WILKINSAffiliation
Clinical And Biomedical SciencesMetadata
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Journal ArticleCitations
Jespersen, S., Berk, M., Van Wyk, C., Dean, O., Dodd, S., Szabo, C. P. & Maud, C. (2004). A pilot randomized, double-blind, placebo-controlled study of granisetron in the treatment of sexual dysfunction in women associated with antidepressant use. INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 19 (3), pp.161-164. https://doi.org/10.1097/00004850-200405000-00007.Access Status
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C1 - Journal Articles Refereed
Abstract
A pilot study was conducted to evaluate the usefulness of granisetron for the treatment of antidepressant induced sexual dysfunction in women. Twelve women with antidepressant induced sexual dysfunction (AISD) were assigned granisetron (n=5) or placebo (n=7) in a 14-day randomized, double-blind, placebo-controlled study. One participant in the granisetron group did not complete the study. Participants were assessed at baseline, day 7 and day 14 using the Feiger Sexual Function and Satisfaction Questionnaire and the Arizona Sexual Experience Scale. No statistical differences were measured at baseline or at endpoint between the granisetron or placebo group. This study did not produce evidence supporting the usefulness of granisetron in AISD.
Keywords
Psychiatry ; Mental HealthExport Reference in RIS Format
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