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    A pilot randomized, double-blind, placebo-controlled study of granisetron in the treatment of sexual dysfunction in women associated with antidepressant use

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    Author
    Jespersen, S; Berk, M; Van Wyk, C; Dean, O; Dodd, S; Szabo, CP; Maud, C
    Date
    2004-05-01
    Source Title
    INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY
    Publisher
    LIPPINCOTT WILLIAMS & WILKINS
    University of Melbourne Author/s
    ORDING-JESPERSEN, SEAN; Berk, Michael; Dean, Olivia; Dodd, Seetal
    Affiliation
    Clinical And Biomedical Sciences
    Metadata
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    Document Type
    Journal Article
    Citations
    Jespersen, S., Berk, M., Van Wyk, C., Dean, O., Dodd, S., Szabo, C. P. & Maud, C. (2004). A pilot randomized, double-blind, placebo-controlled study of granisetron in the treatment of sexual dysfunction in women associated with antidepressant use. INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 19 (3), pp.161-164. https://doi.org/10.1097/00004850-200405000-00007.
    Access Status
    This item is currently not available from this repository
    URI
    http://hdl.handle.net/11343/26376
    DOI
    10.1097/00004850-200405000-00007
    Description

    C1 - Journal Articles Refereed

    Abstract
    A pilot study was conducted to evaluate the usefulness of granisetron for the treatment of antidepressant induced sexual dysfunction in women. Twelve women with antidepressant induced sexual dysfunction (AISD) were assigned granisetron (n=5) or placebo (n=7) in a 14-day randomized, double-blind, placebo-controlled study. One participant in the granisetron group did not complete the study. Participants were assessed at baseline, day 7 and day 14 using the Feiger Sexual Function and Satisfaction Questionnaire and the Arizona Sexual Experience Scale. No statistical differences were measured at baseline or at endpoint between the granisetron or placebo group. This study did not produce evidence supporting the usefulness of granisetron in AISD.
    Keywords
    Psychiatry ; Mental Health

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