Limitations to adaptive optics image quality in rodent eyes
AuthorZhou, X; Bedggood, P; Metha, A
Source TitleBiomedical Optics Express
PublisherOPTICAL SOC AMER
AffiliationOptometry and Vision Sciences
Document TypeJournal Article
CitationsZhou, X., Bedggood, P. & Metha, A. (2012). Limitations to adaptive optics image quality in rodent eyes. BIOMEDICAL OPTICS EXPRESS, 3 (8), pp.1811-1824. https://doi.org/10.1364/BOE.3.001811.
Access StatusOpen Access
Adaptive optics (AO) retinal image quality of rodent eyes is inferior to that of human eyes, despite the promise of greater numerical aperture. This paradox challenges several assumptions commonly made in AO imaging, assumptions which may be invalidated by the very high power and dioptric thickness of the rodent retina. We used optical modeling to compare the performance of rat and human eyes under conditions that tested the validity of these assumptions. Results showed that AO image quality in the human eye is robust to positioning errors of the AO corrector and to differences in imaging depth and wavelength compared to the wavefront beacon. In contrast, image quality in the rat eye declines sharply with each of these manipulations, especially when imaging off-axis. However, some latitude does exist to offset these manipulations against each other to produce good image quality.
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