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A randomized, placebo-controlled phase I trial of DNA prime, recombinant fowlpox virus boost prophylactic vaccine for HIV-1

dc.contributor.authorKelleher, AD
dc.contributor.authorPuls, RL
dc.contributor.authorBebbington, M
dc.contributor.authorBoyle, D
dc.contributor.authorFfrench, R
dc.contributor.authorKent, SJ
dc.contributor.authorKippax, S
dc.contributor.authorPurcell, DFJ
dc.contributor.authorThomson, S
dc.contributor.authorWand, H
dc.contributor.authorCooper, DA
dc.contributor.authorEmery, S
dc.date.available2014-05-21T19:32:30Z
dc.date.issued2006-01-09
dc.identifierpii: 00002030-200601090-00023
dc.identifier.citationKelleher, A. D., Puls, R. L., Bebbington, M., Boyle, D., Ffrench, R., Kent, S. J., Kippax, S., Purcell, D. F. J., Thomson, S., Wand, H., Cooper, D. A. & Emery, S. (2006). A randomized, placebo-controlled phase I trial of DNA prime, recombinant fowlpox virus boost prophylactic vaccine for HIV-1. AIDS, 20 (2), pp.294-297. https://doi.org/10.1097/01.aids.0000199819.40079.e9.
dc.identifier.issn0269-9370
dc.identifier.urihttp://hdl.handle.net/11343/26433
dc.descriptionC1 - Journal Articles Refereed
dc.description.abstractAn HIV-vaccine consisting of a DNA prime, recombinant fowlpox virus (rFPV) boost was evaluated in a double-blind placebo controlled trial. One milligram of pHIS-HIV-B expressing mutated gag, pol, env, vpu, tat and rev was administered at weeks 0 and 4 boosted by 5 x 10(7) pfu rFPV-HIV-B expressing gag/pol at week 8. The vaccine regimen was safe, but there was no difference between vaccine (n = 18) and placebo recipients (n = 6) for Gag or Pol-specific T-cell immune responses at week 9.
dc.formatapplication/pdf
dc.languageEnglish
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.subjectMedical Virology ; Infectious Diseases
dc.titleA randomized, placebo-controlled phase I trial of DNA prime, recombinant fowlpox virus boost prophylactic vaccine for HIV-1
dc.typeJournal Article
dc.identifier.doi10.1097/01.aids.0000199819.40079.e9
melbourne.peerreviewPeer Reviewed
melbourne.affiliationThe University of Melbourne
melbourne.affiliation.departmentMicrobiology And Immunology
melbourne.source.titleAIDS
melbourne.source.volume20
melbourne.source.issue2
melbourne.source.pages294-297
melbourne.publicationid50513
melbourne.elementsid276549
melbourne.contributor.authorKent, Stephen
melbourne.contributor.authorPurcell, Damian
dc.identifier.eissn1473-5571
melbourne.accessrightsThis item is currently not available from this repository


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