Tracking dendritic cells: use of an in situ method to label all blood leukocytes

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    Author
    Ristevski, B; Young, AJ; Dudler, L; Cahill, RNP; Kimpton, W; Washington, E; Hay, JB
    Date
    2003-02-01
    Source Title
    INTERNATIONAL IMMUNOLOGY
    Publisher
    OXFORD UNIV PRESS
    University of Melbourne Author/s
    Kimpton, Wayne; Washington, Elizabeth; CAHILL, ROSS
    Affiliation
    Veterinary Science
    Metadata
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    Document Type
    Journal Article
    Citations
    Ristevski, B., Young, A. J., Dudler, L., Cahill, R. N. P., Kimpton, W., Washington, E. & Hay, J. B. (2003). Tracking dendritic cells: use of an in situ method to label all blood leukocytes. INTERNATIONAL IMMUNOLOGY, 15 (2), pp.159-165. https://doi.org/10.1093/intimm/dxg016.
    Access Status
    This item is currently not available from this repository
    URI
    http://hdl.handle.net/11343/26450
    DOI
    10.1093/intimm/dxg016
    Description

    C1 - Journal Articles Refereed
    Abstract
    Here we describe an in situ procedure with a labeling index (percent of labeled blood leukocytes) >98%, which is high enough to permit the direct tracking of dendritic cell (DC) precursors from blood into lymphoid tissues, while circumventing the pitfalls associated with in vitro labeling. DC and lymphocytes have similar blood to afferent lymph migratory capabilities. This method has additional applications in tracking other rare cell populations in both normal and pathological states.
    Keywords
    Immunology ; Biological Sciences

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