Clinical and immune effects of probiotic and peanut oral immunotherapy for treatment of peanut allergy
Document TypePhD thesis
Access StatusThis item is embargoed and will be available on 2023-03-05.
© 2020 Kuang-Chih Hsiao
Food allergen oral immunotherapy (OIT) is emerging as a potential treatment for food allergy. Probiotic and Peanut Oral Immunotherapy (PPOIT) showed effectiveness inducing non-responsiveness to peanut in the immediate post-treatment period. This doctoral thesis investigates the long-term clinical and immunologic effects of PPOIT in children with peanut allergy and the efficacy and tolerability of a modified PPOIT dose escalation schedule designed to improve treatment feasibility.
KeywordsFood allergy; Peanut allergy; Treatment; Immunotherapy; Oral immunotherapy; Adjuvant; Probiotic and peanut oral immunotherapy (PPOIT); Immune modulation; Desensitisation; Sustained unresponsiveness
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