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dc.contributor.authorGouskos, T
dc.contributor.authorWightman, F
dc.contributor.authorChang, J
dc.contributor.authorEarnest-Silveira, L
dc.contributor.authorSasadeusz, J
dc.contributor.authorLewis, SR
dc.contributor.authorTorresi, J
dc.date.available2014-05-21T19:40:20Z
dc.date.issued2004-08-20
dc.identifierpii: 00002030-200408200-00018
dc.identifier.citationGouskos, T., Wightman, F., Chang, J., Earnest-Silveira, L., Sasadeusz, J., Lewis, S. R. & Torresi, J. (2004). Severe hepatitis and prolonged hepatitis B virus-specific CD8 T-cell response after selection of hepatitis B virus YMDD variant in an HIV/hepatitis B virus-co-infected patient. AIDS, 18 (12), pp.1734-1737. https://doi.org/10.1097/01.aids.0000131384.53350.59.
dc.identifier.issn0269-9370
dc.identifier.urihttp://hdl.handle.net/11343/26613
dc.descriptionC5 - Other Refereed Contribution to Refereed Journals
dc.description.abstractWe describe here a severe flare of hepatitis caused by lamivudine-resistant hepatitis B virus(HBV) in an HIV/HBV co-infected individual.Lamivudine-resistant HBV was detected 6 months before the development of severe hepatitis. Sequencing of the HBV genome isolated from the patients' serum did not identify compensatory mutations in the HBV polymerase that may have restored viral replication. However, a strong HBV-specific CD8 T-cell response was identified and may have resulted in the severe hepatitis.
dc.formatapplication/pdf
dc.languageEnglish
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.subjectInfectious Diseases; Infectious Diseases
dc.titleSevere hepatitis and prolonged hepatitis B virus-specific CD8 T-cell response after selection of hepatitis B virus YMDD variant in an HIV/hepatitis B virus-co-infected patient
dc.typeJournal Article
dc.identifier.doi10.1097/01.aids.0000131384.53350.59
melbourne.peerreviewPeer Reviewed
melbourne.affiliationThe University of Melbourne
melbourne.affiliation.departmentMedicine - Royal Melbourne And Western Hospitals
melbourne.source.titleAIDS
melbourne.source.volume18
melbourne.source.issue12
melbourne.source.pages1734-1737
dc.research.coderfcd321010
dc.research.codeseo1998730101
melbourne.publicationid28802
melbourne.elementsid263463
melbourne.contributor.authorEarnest, Linda
melbourne.contributor.authorSasadeusz, Joseph
melbourne.contributor.authorTorresi, Joseph
melbourne.contributor.authorLewin, Sharon
melbourne.contributor.authorGOUSKOS, THEO
melbourne.contributor.authorWIGHTMAN, FIONA
dc.identifier.eissn1473-5571
melbourne.accessrightsThis item is currently not available from this repository


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