Vector priming reduces the immunogenicity of Salmonella-based vaccines in Nramp1+/+ mice.
Author
Vindurampulle, CJ; Attridge, SRDate
2003-04Source Title
Infection and ImmunityPublisher
American Society for MicrobiologyUniversity of Melbourne Author/s
VINDURAMPULLE, CHRISTOFERAffiliation
Microbiology And ImmunologyMetadata
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Journal ArticleCitations
Vindurampulle, C. J. & Attridge, S. R. (2003). Vector priming reduces the immunogenicity of Salmonella-based vaccines in Nramp1+/+ mice.. Infect Immun, 71 (4), pp.2258-2261. https://doi.org/10.1128/iai.71.4.2258-2261.2003.Access Status
Access this item via the Open Access locationOpen Access at PMC
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC152061Description
C1 - Journal Articles Refereed
Abstract
The present studies in Nramp1(-/-) BALB/c and Nramp1(+/+) CBA mice question the significance of this genotype as a determinant of the level of gut colonization following oral administration of naturally attenuated or highly virulent Salmonella strains. In line with previous results in BALB/c hosts, vector priming of CBA mice with Salmonella enterica serovar Stanley was found to significantly compromise the immunogenicity of a recombinant construct expressing a foreign pilus protein.
Keywords
Bacteriology ; Biological SciencesExport Reference in RIS Format
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