Electrical stimulation of the auditory nerve: stimulus induced reductions in neural excitability [Abstract]

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    Author
    Shepherd, R. K.; Clark, Graeme M.
    Date
    1987
    Source Title
    Proceedings of the Australian Physiological and Pharmacological Society
    University of Melbourne Author/s
    Clark, Graeme; Shepherd, Robert
    Metadata
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    Document Type
    Conference Paper
    Citations
    Shepherd, R. K., & Clark, G. M. (1987). Electrical stimulation of the auditory nerve: stimulus induced reductions in neural excitability [Abstract]. In Proceedings of the Australian Physiological and Pharmacological Society.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/26830
    Description

    This is an abstract of a paper from the Proceedings of the Australian Physiological and Pharmacological Society 1987, published by Australian Physiological and Pharmacological Society. This version is reproduced with the permission of publisher.
    Abstract
    Electrical stimulation of the auditory nerve elicits highly synchronised neural activity (Javel et al., in press). As the stimulus current is increased the neural response becomes highly deterministic with every current pulse eliciting a spike even at stimulus rates of 600-800 pulses per second (pps). Our previous acute experimental studies have shown that high stimulus rates (> 200 pps) and high stimulus currents (> 1.0 mA) can result in temporary and sometimes permanent reductions in the excitability of the auditory nerve (Shepherd and Clark, 1986). The present study was designed to examine the mechanisms underlying these stimulus induced reductions in excitability. These results will have implications for the maximum safe and effective stimulus rates that can be employed in cochlear implants.
    Keywords
    otolaryngology; auditory nerve; cochlear implants

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