Electrical stimulation of the auditory nerve: stimulus induced reductions in neural excitability [Abstract]
AuthorShepherd, R. K.; Clark, Graeme M.
Source TitleProceedings of the Australian Physiological and Pharmacological Society
Document TypeConference Paper
CitationsShepherd, R. K., & Clark, G. M. (1987). Electrical stimulation of the auditory nerve: stimulus induced reductions in neural excitability [Abstract]. In Proceedings of the Australian Physiological and Pharmacological Society.
Access StatusOpen Access
This is an abstract of a paper from the Proceedings of the Australian Physiological and Pharmacological Society 1987, published by Australian Physiological and Pharmacological Society. This version is reproduced with the permission of publisher.
Electrical stimulation of the auditory nerve elicits highly synchronised neural activity (Javel et al., in press). As the stimulus current is increased the neural response becomes highly deterministic with every current pulse eliciting a spike even at stimulus rates of 600-800 pulses per second (pps). Our previous acute experimental studies have shown that high stimulus rates (> 200 pps) and high stimulus currents (> 1.0 mA) can result in temporary and sometimes permanent reductions in the excitability of the auditory nerve (Shepherd and Clark, 1986). The present study was designed to examine the mechanisms underlying these stimulus induced reductions in excitability. These results will have implications for the maximum safe and effective stimulus rates that can be employed in cochlear implants.
Keywordsotolaryngology; auditory nerve; cochlear implants
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- Graeme Clark Collection