neuroBi: A Highly Configurable Neurostimulator for a Retinal Prosthesis and Other Applications
AuthorSlater, KD; Sinclair, NC; Nelson, TS; Blamey, PJ; McDermott, HJ
Source TitleIEEE Journal of Translational Engineering in Health and Medicine
PublisherIEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
University of Melbourne Author/sMcDermott, Hugh; Blamey, Peter; Guymer, Robyn; Opie, Nicholas; Slater, Kyle; Ayton, Lauren
AffiliationAudiology and Speech Pathology
Ophthalmology (Eye & Ear Hospital)
Medicine and Radiology
Optometry and Vision Sciences
Document TypeJournal Article
CitationsSlater, K. D., Sinclair, N. C., Nelson, T. S., Blamey, P. J. & McDermott, H. J. (2015). neuroBi: A Highly Configurable Neurostimulator for a Retinal Prosthesis and Other Applications. IEEE JOURNAL OF TRANSLATIONAL ENGINEERING IN HEALTH AND MEDICINE-JTEHM, 3, https://doi.org/10.1109/JTEHM.2015.2455507.
Access StatusAccess this item via the Open Access location
Open Access URLhttps://europepmc.org/articles/PMC4848081?pdf=render
To evaluate the efficacy of a suprachoroidal retinal prosthesis, a highly configurable external neurostimulator is required. In order to meet functional and safety specifications, it was necessary to develop a custom device. A system is presented which can deliver charge-balanced, constant-current biphasic pulses, with widely adjustable parameters, to arbitrary configurations of output electrodes. This system is shown to be effective in eliciting visual percepts in a patient with approximately 20 years of light perception vision only due to retinitis pigmentosa, using an electrode array implanted in the suprachoroidal space of the eye. The flexibility of the system also makes it suitable for use in a number of other emerging clinical neurostimulation applications, including epileptic seizure suppression and closed-loop deep brain stimulation. Clinical trial registration number NCT01603576 (www.clinicaltrials.gov).
- Click on "Export Reference in RIS Format" and choose "open with... Endnote".
- Click on "Export Reference in RIS Format". Login to Refworks, go to References => Import References
- Minerva Elements Records 
- Optometry and Vision Sciences - Research Publications 
- Medicine and Radiology - Research Publications 
- Ophthalmology (Eye & Ear Hospital) - Research Publications 
- Medical Bionics - Research Publications 
- Audiology and Speech Pathology - Research Publications