Chronic rhinosinusitis and emerging treatment options.

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    Author
    Piromchai, P; Kasemsiri, P; Laohasiriwong, S; Thanaviratananich, S
    Date
    2013
    Source Title
    International Journal of General Medicine
    Publisher
    Informa UK Limited
    University of Melbourne Author/s
    Piromchai, Patorn
    Affiliation
    Otolaryngology
    Metadata
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    Document Type
    Journal Article
    Citations
    Piromchai, P., Kasemsiri, P., Laohasiriwong, S. & Thanaviratananich, S. (2013). Chronic rhinosinusitis and emerging treatment options.. Int J Gen Med, 6, pp.453-464. https://doi.org/10.2147/IJGM.S29977.
    Access Status
    Access this item via the Open Access location
    URI
    http://hdl.handle.net/11343/269406
    DOI
    10.2147/IJGM.S29977
    Open Access URL
    https://europepmc.org/articles/PMC3682850?pdf=render
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682850
    Abstract
    This review describes the epidemiology and various treatments in chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Evidence for short-term use of systemic corticosteroids has been shown to be favorable in CRSwNP, but still limited in CRSsNP. Topical corticosteroids improve symptom scores in both CRS subgroups. The role of microbes in CRS is still controversial. Culture-directed antibiotics are recommended for CRSsNP with exacerbation. Long-term use of low dosage antibiotics is recommended for CRSsNP for their anti-inflammatory effects. Other emerging treatment options are also discussed.

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