Chronic rhinosinusitis and emerging treatment options.
AuthorPiromchai, P; Kasemsiri, P; Laohasiriwong, S; Thanaviratananich, S
Source TitleInternational Journal of General Medicine
PublisherInforma UK Limited
University of Melbourne Author/sPiromchai, Patorn
Document TypeJournal Article
CitationsPiromchai, P., Kasemsiri, P., Laohasiriwong, S. & Thanaviratananich, S. (2013). Chronic rhinosinusitis and emerging treatment options.. Int J Gen Med, 6, pp.453-464. https://doi.org/10.2147/IJGM.S29977.
Access StatusAccess this item via the Open Access location
Open Access URLhttps://europepmc.org/articles/PMC3682850?pdf=render
Open Access at PMChttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682850
This review describes the epidemiology and various treatments in chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). Evidence for short-term use of systemic corticosteroids has been shown to be favorable in CRSwNP, but still limited in CRSsNP. Topical corticosteroids improve symptom scores in both CRS subgroups. The role of microbes in CRS is still controversial. Culture-directed antibiotics are recommended for CRSsNP with exacerbation. Long-term use of low dosage antibiotics is recommended for CRSsNP for their anti-inflammatory effects. Other emerging treatment options are also discussed.
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