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dc.contributor.authorHuang, C. O.en_US
dc.contributor.authorShepherd, Robert K.en_US
dc.contributor.authorSeligman, P. M.en_US
dc.contributor.authorClark, Graeme M.en_US
dc.date.accessioned2014-05-21T19:59:27Z
dc.date.available2014-05-21T19:59:27Z
dc.date.issued1997en_US
dc.identifier.citationHuang, C. O., Shepherd, R. K., Seligman, P. M., & Clark, G. M. (1997). Electrical stimulus induced changes in excitability of the auditory nerve. In Proceedings of the Australian Neuroscience Society, Newcastle.en_US
dc.identifier.urihttp://hdl.handle.net/11343/26992
dc.descriptionThis is an abstract of a paper from Proceedings of the Australian Neuroscience Society 1997 published by Australian Neuroscience Society. This version is reproduced with the permission of publisher.en_US
dc.description.abstractHigh rate electrical stimulation of the auditory nerve using stimulus intensities well above the clinical limits can induce a significant reduction in the excitability of the auditory nerve as measured by a decrement in the amplitude of the electrically evoked auditory brainstem response (EABR). Two potential mechanisms may be associated with this stimulus induced reduction in activity: 1) stimulus induced prolonged neuronal hyperactivity; and 2) the generation of adverse electrochemical productions from the electrode surface. The purpose of the present study was to assess the extent to which adverse electrochemical damage contributes to the stimulus induced reduction in auditory nerve excitability. Twenty-six adult guinea pigs anaesthetized with ketamine (40 mg/kg i.p.) and xylazine (4 mglkg i.p.), were bilaterally implanted and unilaterally stimulated for two hours using a stimulus intensity of two or four times EABR threshold. Stimulus rates of 200, 400, or 1000 pulses/s (pps) were delivered via a standard platinum scala tympani electrode or large surface area ("high Q") platinum electrode.en_US
dc.relation.ispartofScientific publications, vol.10, 1997, no. 1077en_US
dc.subjectcochlear implantsen_US
dc.subjectelectrical stimulationen_US
dc.subjectotolaryngologyen_US
dc.titleElectrical stimulus induced changes in excitability of the auditory nerveen_US
dc.typeConference Itemen_US
melbourne.source.titleProceedings of the Australian Neuroscience Societyen_US
melbourne.source.month2-7 Februaryen_US
melbourne.source.pages8en_US
melbourne.source.locationconferenceNewcastleen_US
dc.description.sourcedateconference2-7 Februaryen_US
melbourne.elementsidNA
melbourne.contributor.authorClark, Graeme
melbourne.contributor.authorHuang, Christie
melbourne.contributor.authorShepherd, Robert
melbourne.contributor.authorSeligman, Peter
melbourne.accessrightsOpen Access


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