Chronic electrical stimulation of the auditory nerve in cats: physiological and histopathological results
AuthorShepherd, R. K.; Clark, Graeme M.; Black, R. C.
Source TitleActa Otolaryngologica
Document TypeJournal Article
CitationsShepherd, R. K., Clark, G. M., & Black, R. C. (1983). Chronic electrical stimulation of the auditory nerve in cats: physiological and histopathological results. Acta Otolaryngologica, Suppl. 399, 19-31.
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The ability of spiral ganglion cells to survive long-term electrical stimulation is a precondition for the success of cochlear prostheses. In this study 10 cats were implanted bilaterally with bipolar scala tympani electrodes and stimulated for periods of up to 2029 hours using charge balanced biphasic current pulses. The status of the auditory nerve was monitored periodically by recording electrically evoked auditory brainstem responses. At the conclusion of the stimulation program, spiral ganglion cell survival was assessed for stimulated and control cochleas; comparison of the two groups showed no statistically significant difference. The results of this study indicate that long-term intracochlear electrical stimulation using carefully controlled biphasic pulses does not adversely affect the spiral ganglion cell population.
Keywordsotolaryngology; spiral ganglion cells; electrical stimulation; cochlear implant
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- Graeme Clark Collection