Melbourne Dental School - Theses
Now showing items 1-10 of 59
Host-pathogen interactions of porphyromonas gingivalis
Periodontal health is supported by various host immune defence mechanisms, which act in concert to maintain host-microbe homeostasis. However, breakdown of homeostasis can lead to the development of chronic periodontitis, ...
Investigations into the effects of head and neck radiotherapy and the potential anticariogenicity of casein phosphopeptide-amorphous calcium phosphate and stannous fluoride
Radiotherapy is the primary treatment modality for most head and neck cancers, in particular, nasopharyngeal carcinoma (NPC). The use of advanced radiotherapy techniques such as intensity modulated radiotherapy (IMRT) ...
Chronic oral Graft-versus-Host Disease: clinical risk factors and biochemical markers of disease activity
Purpose: Allogeneic hematopoietic stem cell transplantation (HSCT), along with the associated immunosuppression required post transplant, is associated with several potentially debilitating long-term complications, one of ...
Enhancing remineralisation using casein phosphopeptide complexes
Casein phosphopeptide (CPP) complexes have been shown to promote remineralisation of dental tissues affected by dental caries. However, remineralisation takes time and can be limited by the delivery and composition of the ...
Biochemical characterisation of outer membrane vesicles from periodontal pathogens and their role in innate immunity
This project characterises and assesses the immunological effects of outer membrane vesicles (OMVs) produced by major periodontal pathogens Porphromonas gingivalis, Treponema denticola and Tannerella forsythia. An OMV ...
Comparative studies of demarcated hypomineralised lesions of dental enamel and their fluorescence properties
Demarcated hypomineralised lesions (DHL) of dental enamel are qualitative developmental defects including molar-incisor hypomineralisation (MIH), hypomineralised second primary molars (HSPM) as well as other demarcated ...
Characterisation of Candida albicans, Actinomyces naeslundii and Streptococcus mutans interaction and its role in promoting oral carcinogenesis
Candida albicans has been widely reported in the aetiology of oral cancer. However, the role of its interaction with members of the oral microbiome, such as Actinomyces naeslundii and Streptococcus mutans, in promoting ...
Effect of exposure of glass ionomer cements to acid environments
This research focused on evaluating the effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) incorporated into a glass ionomer cement (GIC). Two conventional GIC materials were the main focus of the study, ...
Influence of the addition of microencapsulated phytoncide to a denture base resin on mechanical properties and antimicrobial activity
Background: Resins such as a polymethyl methacrylate (PMMA) are the most commonly used in denture base material (DBR) because it possesses the advantage of adequate physical, mechanical, and aesthetic properties. However, ...
Dental hospitalisation of Victorian children and young adults - prevalence, determinants, impacts and policy implications
The number of Victorians who have had dental care under a general anaesthetic (DGA) has increased over the last 15 years. This procedure is necessary for dental treatment for some people. It is also costly and although ...