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dc.contributor.authorFranz, B.en_US
dc.contributor.authorClark, Graeme M.en_US
dc.contributor.authorBloom, D. M.en_US
dc.date.accessioned2014-05-21T20:11:24Z
dc.date.available2014-05-21T20:11:24Z
dc.date.issued1984en_US
dc.identifier.citationFranz, B., Clark, G. M., & Bloom, D. M. (1984). Permeability of the implanted round window membrane in the cat: an investigation using horseradish peroxidase. Acta Otolaryngologica, (suppl. 410), 17-23.en_US
dc.identifier.urihttp://hdl.handle.net/11343/27204
dc.descriptionPublisher’s permission requested and denied.en_US
dc.description.abstractThe round window membrane of seven cats was implanted with a Silastic® prosthesis 5 mm long. The membrane's permeability to horseradish peroxidase was investigated at different stages after implantation. All cats were treated with amoxycillin for a period of one week after the operation. Results showed an increased permeability over a period of approximately two weeks following implantation. Thereafter the round window barrier to horseradish peroxidase returned to normal. In all cases cochlear hair cells and auditory nerve fibres were preserved. In cases of spontaneous infection in the bulla the membrane responded with a proliferation of the subepithelial connective tissue, and the formation of protuberances. In these round windows although the permeability was increased the penetration of horseradish peroxidase into the scala tympani was limited. Horseradish peroxidase always passed through the gap between the membrane and the prosthesis. Particles were taken up, however, by the connective tissue envelope that formed around the prosthesis after one week.en_US
dc.relation.ispartofScientific publications, vol.3, 1984-1986, no.161en_US
dc.subjectcochlear implanten_US
dc.subjecthorseradish peroxidaseen_US
dc.subjectpermeabilityen_US
dc.subjectprosthesisen_US
dc.subjectround window membraneen_US
dc.titlePermeability of the implanted round window membrane in the cat: an investigation using horseradish peroxidaseen_US
dc.typeJournal Articleen_US
melbourne.source.titleActa Otolaryngologicaen_US
melbourne.source.issuesuppl. 410en_US
melbourne.source.pages17-23en_US
melbourne.elementsidNA
melbourne.contributor.authorClark, Graeme
melbourne.contributor.authorFranz, Burkhard
melbourne.accessrightsThis item is currently not available from this repository


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