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dc.contributor.authorRubinstein, NJ
dc.contributor.authorTurpin, A
dc.contributor.authorDenniss, J
dc.contributor.authorMcKendrick, AM
dc.date.accessioned2021-05-03T23:59:09Z
dc.date.available2021-05-03T23:59:09Z
dc.date.issued2021-01-01
dc.identifierpii: TVST-20-2282
dc.identifier.citationRubinstein, N. J., Turpin, A., Denniss, J. & McKendrick, A. M. (2021). Effects of Criterion Bias on Perimetric Sensitivity and Response Variability in Glaucoma. TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 10 (1), https://doi.org/10.1167/tvst.10.1.18.
dc.identifier.issn2164-2591
dc.identifier.urihttp://hdl.handle.net/11343/272791
dc.description.abstractPurpose: The purpose of this study was to isolate and quantify the effects of observer response criterion on perimetric sensitivity, response variability, and maximum response probability. Methods: Twelve people with glaucoma were tested at three locations in the visual field (age = 47-77 years, mean deviation = -0.61 to -14.54 dB, test location Humphrey field analyzer [HFA] sensitivities = 1 to 30 dB). Frequency of seeing (FoS) curves were measured using a method of constant stimuli with two response paradigms: a "yes-no" paradigm similar to static automated perimetry and a criterion-free two interval forced choice (2IFC) paradigm. Comparison measures of sensitivity, maximum response probability, and response variability were derived from the fitted FoS curves. Results: Sensitivity differences between the tasks varied widely (range = -11.3 dB to 21.6 dB) and did not correlate with visual field sensitivity nor whether the visual field location was in an area of steep sensitivity gradient within the visual field. Due to the wide variation in differences between the methods, there was no significant difference in mean sensitivity between the 2IFC task relative to the yes-no task, but a trend for higher sensitivity (mean = 1.9 dB, SD = 6.0 dB, P = 0.11). Response variability and maximum response probability did not differ between the tasks (P > 0.99 and 0.95, respectively). Conclusions: Perimetric sensitivity estimates are demonstrably altered by observer response criterion but the effect varies widely and unpredictably, even within a single test. Response bias should be considered a factor in perimetric test variability and when comparing sensitivities to nonperimetric data. Translational Relevance: The effect of response criterion on perimetric response variability varies widely and unpredictably, even within a single test.
dc.languageEnglish
dc.publisherASSOC RESEARCH VISION OPHTHALMOLOGY INC
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0
dc.titleEffects of Criterion Bias on Perimetric Sensitivity and Response Variability in Glaucoma
dc.typeJournal Article
dc.identifier.doi10.1167/tvst.10.1.18
melbourne.affiliation.departmentOptometry and Vision Sciences
melbourne.affiliation.departmentChancellery Research
melbourne.affiliation.facultyScience
melbourne.affiliation.facultyChancellery
melbourne.source.titleTranslational Vision Science and Technology
melbourne.source.volume10
melbourne.source.issue1
melbourne.identifier.arcLP130100055
melbourne.identifier.arcLP150100815
dc.rights.licenseCC BY-NC-ND
melbourne.elementsid1492697
melbourne.contributor.authorTurpin, Andrew
melbourne.contributor.authorMcKendrick, Allison
dc.identifier.eissn2164-2591
melbourne.identifier.fundernameidAUST RESEARCH COUNCIL, LP130100055
melbourne.identifier.fundernameidAUST RESEARCH COUNCIL, LP150100815
melbourne.accessrightsOpen Access


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