Sir Peter MacCallum Department of Oncology
Collections in this community
Investigating epigenetic perturbations associated with DNMT3A and BCOR mutations in normal and malignant haematopoiesis (2019)Despite recent advances in cancer detection, molecular classification and treatment modalities, the 5-year survival rate of acute myeloid leukaemia (AML) has not changed in 30 years. The unique genetic context created by ...
Immune markers to predict response to neoadjuvant chemoradiotherapy and identifying methods to incorporate immunotherapy in locally advanced rectal cancer (2018)The standard of care for locally advanced rectal cancer (T3-4 +/- N+) is neoadjuvant chemoradiotherapy (CRT) followed by total mesorectal excision (TME). However, this has been challenged recently with increasing interest ...
(2018)Cancer progression is invariably associated with changes in the stromal microenvironment, most notably, the extracellular matrix (ECM) composition. Laminins (LM) are a family of large trimeric ECM proteins comprised of at ...