Animal models of human disease: otitis media
AuthorFranz, Burkhard K-H. G.; Shepherd, Robert K.; Clark, Graeme M.
Source TitleComparative Pathology Bulletin
Document TypeJournal Article
CitationsFranz, B. K-H. G., Shepherd, R. K., & Clark, G. M. (1991). Animal models of human disease: otitis media. Comparative Pathology Bulletin, February, 23, 2,6.
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Otitis media is an inflammation of the middle ear, which may or may not be of microbial origin. Genetic, immunologic, allergic conditions, antecedent viral respiratory infections, and mastoid size are contributing factors for middle ear disease. Dysfunction of the eustachian tube predisposes to acute otitis media. Collection of fluid within the middle ear cavity is part of the disease process and is equally observed in infectious and noninfectious middle ear disease. Streptococcus pneumonia, Haemophilus influenza, Streptococcus pyogenes, and Streptococcus aureus are the most common organisms that cause acute infectious otitis media.
Keywordsotolaryngology; human disease; otitis media; animal model
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- Graeme Clark Collection