A gated differential amplifier for recording physiological responses to electrical stimulation
AuthorMillard, Rodney E.; McAnally, Ken I.; Clark, Graeme M.
Source TitleJournal of Neuroscience Methods
Document TypeJournal Article
CitationsMillard, R. E., McAnally, K. I., & Clark, G. M. (1992). A gated differential amplifier for recording physiological responses to electrical stimulation. Journal of Neuroscience Methods, June, 44, 81-84.
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Artifact from electrical stimulation imposes a problem for the recording of physiological responses to electrical stimulation. Here we describe a simple, low-cost, gated differential amplifier for the recording of physiological responses to electrical stimulation. The gain of the amplifier is set to 1 during electrical stimulation by setting the gate input to a high logic state to avoid overloading of the amplifier by the artifact. Following electrical stimulation, the gate input is set to a low logic state, resulting in again of 1000 for frequencies between 300 Hz and 25 kHz ( -3 dB points). The gain at low frequencies (0-0.2 Hz) is held constant at 1 to avoid transients in the output signal arising from changes in gain at these frequencies. The gain of the amplifier following stimulation (gate low) was independent of the magnitude of the artifact and was therefore suitable for the measurement of neural field potentials with low impedance electrodes.
Keywordsamplification; electrical stimulation; stimulation artefact; physiological recording
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- Graeme Clark Collection