Acute effects of high-rate stimulation on auditory nerve function in guinea pigs
AuthorTykocinski, M.; Shepherd, R. K.; Clark, Graeme M.
Source TitleAnnals of Otology, Rhinology & Laryngology
Document TypeJournal Article
CitationsTykocinski, M., Shepherd, R. K., & Clark, G. M. (1995). Acute effects of high-rate stimulation on auditory nerve function in guinea pigs. Annals of Otology, Rhinology & Laryngology, 104(suppl.166), 71-74.
Access StatusOpen Access
This is a publisher’s version of an article published in Annals of Otology, Rhinology & Laryngology published by Annals Publishing Company. This version is reproduced with permission from Annals Publishing Company. http://www.annals.com/
Cochlear implants have been shown to successfully provide profoundly deaf patients with auditory cues for speech discrimination. Furthermore, a number of safety studies using the Melbourne/Cochlear electrode array indicated that chronic electrical stimulation using charge-balanced biphasic current pulses and stimulus rates between 100 and 500 pulses per second (pps) do not result in additional spiral ganglion loss or general cochlear pathology.1-3 However, safe maximum levels for stimulus parameters (stimulus rate, charge per phase, charge density) have not yet been adequately defined.
Keywordscochlear implants; auditory nerve function; guinea pig; deafness; speech discrimination; electrical stimulation
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- Graeme Clark Collection