Supporting grid-based clinical trials in Scotland
AuthorSinnott, R. O.; Stell, A. J.; Ajayi, O.
Source TitleHealth Informatics Journal
Document TypeJournal Article
CitationsSinnott, R. O., Stell, A. J., & Ajayi, O. (2008). Supporting grid-based clinical trials in Scotland. Health Informatics Journal, 14(2), 79-93.
Access StatusOpen Access
The final, definitive version of this paper has been published in Health Informatics Journal, Vol 14/Issue2, 2008 by SAGE Publications Ltd, All rights reserved. © SAGE Publications Ltd.
A computational infrastructure to underpin complex clinical trials and medical population studies is highly desirable. This should allow access to a range of distributed clinical data sets; support the effi cient processing and analysis of the data obtained; have security at its heart; and ensure that authorized individuals are able to see privileged data and no more. Each clinical trial has its own requirements on data sets and how they are used; hence a reusable and fl exible framework offers many advantages. The MRC funded Virtual Organisations for Trials and Epidemiological Studies (VOTES) is a collaborative project involving several UK universities specifi cally to explore this space. This article presents the experiences of developing the Scottish component of this nationwide infrastructure, by the National e-Science Centre (NeSC) based at the University of Glasgow, and the issues inherent in accessing and using the clinical data sets in a fl exible, dynamic and secure manner.
Keywordsclinical trials; data federation; grid; security
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