The origins of SARS-CoV-2: A critical review

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    Author
    Holmes, EC; Goldstein, SA; Rasmussen, AL; Robertson, DL; Crits-Christoph, A; Wertheim, JO; Anthony, SJ; Barclay, WS; Boni, MF; Doherty, PC; ...
    Date
    2021-09-16
    Source Title
    Cell
    Publisher
    CELL PRESS
    University of Melbourne Author/s
    Doherty, Peter
    Affiliation
    Microbiology and Immunology
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Holmes, E. C., Goldstein, S. A., Rasmussen, A. L., Robertson, D. L., Crits-Christoph, A., Wertheim, J. O., Anthony, S. J., Barclay, W. S., Boni, M. F., Doherty, P. C., Farrar, J., Geoghegan, J. L., Jiang, X., Leibowitz, J. L., Neil, S. J. D., Skern, T., Weiss, S. R., Worobey, M., Andersen, K. G. ,... Rambaut, A. (2021). The origins of SARS-CoV-2: A critical review. CELL, 184 (19), pp.4848-4856. https://doi.org/10.1016/j.cell.2021.08.017.
    Access Status
    Access this item via the Open Access location
    URI
    http://hdl.handle.net/11343/288085
    DOI
    10.1016/j.cell.2021.08.017
    Open Access URL
    Published version
    Open Access at PMC
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373617
    Abstract
    Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the human population. Recent debate has coalesced around two competing ideas: a "laboratory escape" scenario and zoonotic emergence. Here, we critically review the current scientific evidence that may help clarify the origin of SARS-CoV-2.

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