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    Development of grid frameworks for clinical trials and epidemiological studies

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    Development of grid frameworks for clinical trials and epidemiological studies (614.2Kb)

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    Author
    SINNOTT, RICHARD; STELL, ANTHONY; Ajayi, Oluwafemi
    Date
    2006
    Source Title
    Studies in Health Technology and Informatics
    Publisher
    IOS Press
    University of Melbourne Author/s
    Sinnott, Richard; Stell, Anthony
    Metadata
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    Document Type
    Journal Article
    Citations
    Sinnott, R., Stell, A., & Ajayi, O. (2006). Development of grid frameworks for clinical trials and epidemiological studies. Studies in Health Technology and Informatics, 120, 117-130.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/28868
    Description

    This is a post-print of an article published in Studies in Health Technology and Informatics 2006 published by IOS Press. http://iospress.metapress.com/content/bfx1qck28a16/?sortorder=asc&p_o=10

    Abstract
    E-Health initiatives such as electronic clinical trials and epidemiological studies require access to and usage of a range of both clinical and other data sets. Such data sets are typically only available over many heterogeneous domains where a plethora of often legacy based or in-house/bespoke IT solutions exist. Considerable efforts and investments are being made across the UK to upgrade the IT infrastructures across the National Health Service (NHS) such as the National Program for IT in the NHS (NPFIT) [1]. However, it is the case that currently independent and largely non-interoperable IT solutions exist across hospitals, trusts, disease registries and GP practices – this includes security as well as more general compute and data infrastructures. Grid technology allows issues of distribution and heterogeneity to be overcome, however the clinical trials domain places special demands on security and data which hitherto the Grid community have not satisfactorily addressed. These challenges are often common across many studies and trials hence the development of a re-usable framework for creation and subsequent management of such infrastructures is highly desirable. In this paper we present the challenges in developing such a framework and outline initial scenarios and prototypes developed within the MRC funded Virtual Organisations for Trials and Epidemiological Studies (VOTES) project [2].
    Keywords
    clinical trials; Grid technology

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