Show simple item record

dc.contributor.authorMcNamara, HC
dc.contributor.authorFrawley, HC
dc.contributor.authorDonoghue, JF
dc.contributor.authorReadman, E
dc.contributor.authorHealey, M
dc.contributor.authorEllett, L
dc.contributor.authorReddington, C
dc.contributor.authorHicks, LJ
dc.contributor.authorHarlow, K
dc.contributor.authorRogers, PAW
dc.contributor.authorCheng, C
dc.date.accessioned2021-10-25T04:03:04Z
dc.date.available2021-10-25T04:03:04Z
dc.date.issued2021-09-01
dc.identifier.citationMcNamara, H. C., Frawley, H. C., Donoghue, J. F., Readman, E., Healey, M., Ellett, L., Reddington, C., Hicks, L. J., Harlow, K., Rogers, P. A. W. & Cheng, C. (2021). Peripheral, Central, and Cross Sensitization in Endometriosis-Associated Pain and Comorbid Pain Syndromes. Frontiers in Reproductive Health, 3, pp.729642-. https://doi.org/10.3389/frph.2021.729642.
dc.identifier.issn2673-3153
dc.identifier.urihttp://hdl.handle.net/11343/289772
dc.description.abstractEndometriosis-associated pain and the mechanisms responsible for its initiation and persistence are complex and difficult to treat. Endometriosis-associated pain is experienced as dysmenorrhea, cyclical pain related to organ function including dysuria, dyschezia and dyspareunia, and persistent pelvic pain. Pain symptomatology correlates poorly with the extent of macroscopic disease. In addition to the local effects of disease, endometriosis-associated pain develops as a product of peripheral sensitization, central sensitization and cross sensitization. Endometriosis-associated pain is further contributed to by comorbid pain conditions, such as bladder pain syndrome, irritable bowel syndrome, abdomino-pelvic myalgia and vulvodynia. This article will review endometriosis-associated pain, its mechanisms, and its comorbid pain syndromes with a view to aiding the clinician in navigating the literature and terminology of pain and pain syndromes. Limitations of our current understanding of endometriosis-associated pain will be acknowledged. Where possible, commonalities in pain mechanisms between endometriosis-associated pain and comorbid pain syndromes will be highlighted.
dc.publisherFrontiers Media SA
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titlePeripheral, Central, and Cross Sensitization in Endometriosis-Associated Pain and Comorbid Pain Syndromes
dc.typeJournal Article
dc.identifier.doi10.3389/frph.2021.729642
melbourne.affiliation.departmentObstetrics and Gynaecology
melbourne.affiliation.departmentMelbourne School of Health Sciences
melbourne.affiliation.facultyMedicine, Dentistry & Health Sciences
melbourne.source.titleFrontiers in Reproductive Health
melbourne.source.volume3
melbourne.source.pages729642-
dc.rights.licenseCC BY
melbourne.elementsid1595314
melbourne.contributor.authorDonoghue, Jacqueline
melbourne.contributor.authorFrawley, Helena
melbourne.contributor.authorRogers, Peter
melbourne.contributor.authorReddington, Charlotte
dc.identifier.eissn2673-3153
melbourne.accessrightsOpen Access


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record