Management of Early Node-Positive Breast Cancer in Australia: A Multicentre Study

    Thumbnail
    Download
    Citations
    Scopus
    Altmetric
    8
    Author
    Gannan, E; Khoo, J; Nightingale, S; Suhardja, TS; Lippey, J; Keane, H; Tan, KJ; Clouston, D; Gorelik, A; Mann, GB
    Date
    2016-07-01
    Source Title
    The Breast Journal
    Publisher
    WILEY
    University of Melbourne Author/s
    Gorelik, Alexandra; Henderson, Michael; Mann, Gregory; TAN, KIAN; Nightingale, Sophie; Lippey, Jocelyn
    Affiliation
    Melbourne Graduate School of Education
    Medical Education
    Medicine (RMH)
    Surgery (RMH)
    Surgery (St Vincent's)
    Surgery (Western Health)
    Metadata
    Show full item record
    Document Type
    Journal Article
    Citations
    Gannan, E., Khoo, J., Nightingale, S., Suhardja, T. S., Lippey, J., Keane, H., Tan, K. J., Clouston, D., Gorelik, A. & Mann, G. B. (2016). Management of Early Node-Positive Breast Cancer in Australia: A Multicentre Study. BREAST JOURNAL, 22 (4), pp.413-419. https://doi.org/10.1111/tbj.12595.
    Access Status
    Open Access
    URI
    http://hdl.handle.net/11343/291188
    DOI
    10.1111/tbj.12595
    Abstract
    To examine practice patterns for breast cancer patients with limited sentinel node (SN) disease in light of the ACOSOG Z0011 results. Retrospective analysis of patients with T1-2 breast cancer and positive sentinel lymph node biopsy (SLNB) admitted between January 2009 and December 2012. Patient demographics, tumor characteristics, and treatments were recorded. Eight hundred positive SLNBs were identified. A total of 452 (56.5%) proceeded to completion axillary lymph node dissection (cALND). cALND rate decreased from 65.1% to 49.7% from 2009-2010 to 2011-2012. cALND was performed for micrometastasis or isolated tumor cells in 39.3% in 2009-2010 and 22.2% in 2011-2012, whereas for macrometastases the rates were 83.1% and 68.6%, respectively. cALND rates diminished for both Z0011-eligible and -ineligible patients. The ACOSOG Z0011 trial presentation and publication coincided with a reduction in cALND for breast cancer with limited nodal disease. There appears equipoise regarding management of macrometastatic SN disease.

    Export Reference in RIS Format     

    Collections