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dc.contributor.authorHarris, PJ
dc.contributor.authorBuyya, R
dc.contributor.authorChu, X
dc.contributor.authorKobialka, T
dc.contributor.authorKazmierczak, E
dc.contributor.authorMoss, R
dc.contributor.authorAppelbe, W
dc.contributor.authorHunter, PJ
dc.contributor.authorThomas, SR
dc.date.available2014-05-21T23:01:20Z
dc.date.issued2009-06-13
dc.identifierpii: 367/1896/2141
dc.identifier.citationHarris, P. J., Buyya, R., Chu, X., Kobialka, T., Kazmierczak, E., Moss, R., Appelbe, W., Hunter, P. J. & Thomas, S. R. (2009). The Virtual Kidney: an eScience interface and Grid portal. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 367 (1896), pp.2141-2159. https://doi.org/10.1098/rsta.2008.0291.
dc.identifier.issn1364-503X
dc.identifier.urihttp://hdl.handle.net/11343/29396
dc.description.abstractThe Virtual Kidney uses a web interface and distributed computing to provide experimental scientists and analysts with access to computational simulations and knowledge databases hosted in geographically separated laboratories. Users can explore a variety of complex models without requiring the specific programming environment in which applications have been developed. This initiative exploits high-bandwidth communication networks for collaborative research and for shared access to knowledge resources. The Virtual Kidney has been developed within a specialist community of renal scientists but is transferable to other areas of research requiring interaction between published literature and databases, theoretical models and simulations and the formulation of effective experimental designs. A web-based three-dimensional interface provides access to experimental data, a parameter database and mathematical models. A multi-scale kidney reconstruction includes blood vessels and serially sectioned nephrons. Selection of structures provides links to the database, returning parameter values and extracts from the literature. Models are run locally or remotely with a Grid resource broker managing scheduling, monitoring and visualization of simulation results and application, credential and resource allocation. Simulation results are viewed graphically or as scaled colour gradients on the Virtual Kidney structures, allowing visual and quantitative appreciation of the effects of simulated parameter changes.
dc.languageEnglish
dc.publisherROYAL SOC
dc.subjectComputer Software
dc.titleThe Virtual Kidney: an eScience interface and Grid portal
dc.typeJournal Article
dc.identifier.doi10.1098/rsta.2008.0291
melbourne.peerreviewPeer Reviewed
melbourne.affiliationThe University of Melbourne
melbourne.affiliation.departmentComputer Science and Software Engineering
melbourne.source.titlePHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
melbourne.source.volume367
melbourne.source.issue1896
melbourne.source.pages2141-2159
dc.research.codefor803
dc.description.pagestart2141
melbourne.publicationid132016
melbourne.elementsid314419
melbourne.contributor.authorHARRIS, PETER
melbourne.contributor.authorBuyya, Rajkumar
melbourne.contributor.authorMoss, Robert
melbourne.contributor.authorKazmierczak, Edmund
melbourne.contributor.authorCHU, XINGCHEN
melbourne.contributor.authorKOBIALKA, TOMASZ
dc.identifier.eissn1471-2962
melbourne.conference.locationEngland
melbourne.accessrightsThis item is currently not available from this repository


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