Optometry and Vision Sciences - Research Publications
Now showing items 1-10 of 176
Susceptibility of Streptozotocin-Induced Diabetic Rat Retinal Function and Ocular Blood Flow to Acute Intraocular Pressure Challenge
(ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013-03-01)
PURPOSE. To consider the hypothesis that streptozotocin (STZ)-induced hyperglycemia renders rat retinal function and ocular blood flow more susceptible to acute IOP challenge.METHODS. Retinal function (electroretinogram ...
Multiple pathways carry signals from short-wavelength-sensitive ('blue') cones to the middle temporal area of the macaque
We recorded spike activity of single neurones in the middle temporal visual cortical area (MT or V5) of anaesthetised macaque monkeys. We used flashing, stationary spatially circumscribed, cone-isolating and luminance-modulated ...
Eyes in Various Species Can Shorten to Compensate for Myopic Defocus
(ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013-04-27)
PURPOSE. We demonstrated that eyes of young animals of various species (chick, tree shrew, marmoset, and rhesus macaque) can shorten in the axial dimension in response to myopic defocus.METHODS. Chicks wore positive or ...
Intrinsic physiological properties of rat retinal ganglion cells with a comparative analysis
(AMER PHYSIOLOGICAL SOC, 2012-10-27)
Wong RC, Cloherty SL, Ibbotson MR, O' Brien BJ. Intrinsic physiological properties of rat retinal ganglion cells with a comparative analysis. J Neurophysiol 108: 2008-2023, 2012. First published July 11, 2012; doi: ...
Electroretinography in streptozotocin diabetic rats following acute intraocular pressure elevation
Background: We consider whether pre-existing streptozotocin induced hyperglycemia in rats affects the ability of the eye to cope with a single episode of acute intraocular pressure (IOP) elevation. ...
Increased susceptibility to injury in older eyes
(Lippincott Williams & Wilkins, 2013)
Purpose: To determine whether there is an age-dependent susceptibility in retinal function in response to repeated anterior chamber cannulation with or without intraocular pressure (IOP) elevation. ...
Functional changes in the retina during and following acute intraocular pressure elevation in mice
(Association for Research in Vision and Ophthalmology (ARVO), 2009)
Purpose: To examine retinal function using the full-field electroretinogram (ERG) during and after acute intraocular pressure (IOP) elevation in wild-type mice. Methods: IOP ...
Effect of acute intraocular pressure challenge on rat retinal and cortical function
(Association for Research in Vision and Ophthalmology (ARVO), 2014)
Purpose: The global or gross response index of visual performance measured from the eye does not necessarily translate to global responses measured from the brain. A better understanding of this relationship would facilitate ...
Susceptibility of streptozotocin-induced diabetic rat retinal function and ocular blood flow to acute intraocular pressure challenge
(Association for Research in Vision and Ophthalmology (ARVO), 2013)
Purpose: To consider the hypothesis that streptozotocin (STZ)-induced hyperglycemia renders rat retinal function and ocular blood flow more susceptible to acute IOP challenge. ...
Coupling blood flow and neural function in the retina: a model for homeostatic responses to ocular perfusion pressure challenge
(Wiley Periodicals, Inc., 2013)
Retinal function is known to be more resistant than blood flow to acute reduction of ocular perfusion pressure (OPP). To understand the mechanisms underlying the disconnect between blood flow and neural function, a ...