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dc.contributor.authorKnox, J
dc.contributor.authorCowan, RU
dc.contributor.authorDoyle, JS
dc.contributor.authorLigtermoet, MK
dc.contributor.authorArcher, JS
dc.contributor.authorBurrow, JNC
dc.contributor.authorTong, SYC
dc.contributor.authorCurrie, BJ
dc.contributor.authorMackenzie, JS
dc.contributor.authorSmith, DW
dc.contributor.authorCatton, M
dc.contributor.authorMoran, RJ
dc.contributor.authorAboltins, CA
dc.contributor.authorRichards, JS
dc.identifierpii: kno11026_fm
dc.identifier.citationKnox, J., Cowan, R. U., Doyle, J. S., Ligtermoet, M. K., Archer, J. S., Burrow, J. N. C., Tong, S. Y. C., Currie, B. J., Mackenzie, J. S., Smith, D. W., Catton, M., Moran, R. J., Aboltins, C. A. & Richards, J. S. (2012). Murray Valley encephalitis: a review of clinical features, diagnosis and treatment. MEDICAL JOURNAL OF AUSTRALIA, 196 (5), pp.322-326.
dc.descriptionC1 - Journal Articles Refereed
dc.description.abstractMurray Valley encephalitis virus (MVEV) is a mosquito-borne virus that is found across Australia, Papua New Guinea and Irian Jaya. MVEV is endemic to northern Australia and causes occasional outbreaks across south-eastern Australia. 2011 saw a dramatic increase in MVEV activity in endemic regions and the re-emergence of MVEV in south-eastern Australia. This followed significant regional flooding and increased numbers of the main mosquito vector, Culex annulirostris, and was evident from the widespread seroconversion of sentinel chickens, fatalities among horses and several cases in humans, resulting in at least three deaths. The last major outbreak in Australia was in 1974, during which 58 cases were identified and the mortality rate was about 20%. With the potential for a further outbreak of MVEV in the 2011-2012 summer and following autumn, we highlight the importance of this disease, its clinical characteristics and radiological and laboratory features. We present a suspected but unproven case of MVEV infection to illustrate some of the challenges in clinical management. It remains difficult to establish an early diagnosis of MVEV infection, and there is a lack of proven therapeutic options.
dc.subjectInfectious Diseases; Neurology and Neuromuscular Diseases; Nervous System and Disorders; Disease Distribution and Transmission (incl. Surveillance and Response)
dc.titleMurray Valley encephalitis: a review of clinical features, diagnosis and treatment
dc.typeJournal Article
melbourne.peerreviewPeer Reviewed
melbourne.affiliationThe University of Melbourne
melbourne.affiliation.departmentMedicine - Austin Health
melbourne.source.titleMedical Journal of Australia
melbourne.contributor.authorArcher, John
melbourne.contributor.authorAboltins, Craig
melbourne.contributor.authorRichards, Jack
melbourne.contributor.authorTong, Steven
melbourne.fieldofresearch320211 Infectious diseases
melbourne.fieldofresearch320905 Neurology and neuromuscular diseases
melbourne.seocode200199 Clinical health not elsewhere classified
melbourne.seocode200404 Disease distribution and transmission (incl. surveillance and response)
melbourne.accessrightsThis item is currently not available from this repository

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