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Newly Emerging Clones of Bordetella pertussis Carrying prn2 and ptxP3 Alleles Implicated in Australian Pertussis Epidemic in 2008-2010

dc.contributor.authorOctavia, S
dc.contributor.authorSintchenko, V
dc.contributor.authorGilbert, GL
dc.contributor.authorLawrence, A
dc.contributor.authorKeil, AD
dc.contributor.authorHogg, G
dc.contributor.authorLan, R
dc.date.available2014-05-22T07:35:52Z
dc.date.issued2012-04-15
dc.identifierpii: jis178
dc.identifier.citationOctavia, S., Sintchenko, V., Gilbert, G. L., Lawrence, A., Keil, A. D., Hogg, G. & Lan, R. (2012). Newly Emerging Clones of Bordetella pertussis Carrying prn2 and ptxP3 Alleles Implicated in Australian Pertussis Epidemic in 2008-2010. JOURNAL OF INFECTIOUS DISEASES, 205 (8), pp.1220-1224. https://doi.org/10.1093/infdis/jis178.
dc.identifier.issn0022-1899
dc.identifier.urihttp://hdl.handle.net/11343/32962
dc.descriptionC1 - Journal Articles Refereed
dc.description.abstractAustralia is experiencing a prolonged epidemic of pertussis that began in 2008. A total of 194 Bordetella pertussis isolates collected from 2008 through 2010 were typed by single-nucleotide polymorphism (SNP) analysis, by multilocus variable number tandem repeats analysis, and by fim3, prn, and ptxP sequence analyses. Strains with 2 closely related SNP profiles carrying prn2 and ptxP3 from the recently emerged SNP cluster I predominated. The data suggest increasing selection among the B. pertussis population in Australia in favor of strains carrying prn2 and ptxP3 under the pressure of acellular vaccine-induced immunity.
dc.languageEnglish
dc.publisherOXFORD UNIV PRESS INC
dc.subjectPublic Health and Health Services not elsewhere classified; Public Health (excl. Specific Population Health) not elsewhere classified
dc.titleNewly Emerging Clones of Bordetella pertussis Carrying prn2 and ptxP3 Alleles Implicated in Australian Pertussis Epidemic in 2008-2010
dc.typeJournal Article
dc.identifier.doi10.1093/infdis/jis178
melbourne.peerreviewPeer Reviewed
melbourne.affiliationThe University of Melbourne
melbourne.affiliation.departmentMdu Microbiology
melbourne.source.titleJOURNAL OF INFECTIOUS DISEASES
melbourne.source.volume205
melbourne.source.issue8
melbourne.source.pages1220-1224
melbourne.publicationid184920
melbourne.elementsid408897
melbourne.contributor.authorHOGG, GEOFFREY
dc.identifier.eissn1537-6613
melbourne.fieldofresearch420699 Public health not elsewhere classified
melbourne.seocode200499 Public health (excl. specific population health) not elsewhere classified
melbourne.accessrightsThis item is currently not available from this repository


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