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dc.contributor.authorOnimaru, H
dc.contributor.authorDutschmann, M
dc.date.available2014-05-22T08:18:28Z
dc.date.available2011-10-18
dc.date.issued2012-01-01
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000298600800009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4d813f4571fa7d6246bdc0dfeca3a1c
dc.identifier.citationOnimaru, H. & Dutschmann, M. (2012). Calcium imaging of neuronal activity in the most rostral parafacial respiratory group of the newborn rat. JOURNAL OF PHYSIOLOGICAL SCIENCES, 62 (1), pp.71-77. https://doi.org/10.1007/s12576-011-0179-2.
dc.identifier.issn1880-6546
dc.identifier.urihttp://hdl.handle.net/11343/33194
dc.descriptionC1 - Journal Articles Refereed
dc.description.abstractThe parafacial respiratory group (pFRG) is thought to be involved in respiratory rhythm generation in neonates. This subgroup expresses the transcription factor, Phox2b, and contains intrinsically CO(2) sensitive neurons. Calcium imaging has been widely used for analysis of neuronal activity at the cellular and network level. In the present study, we applied calcium imaging to analyze neuronal activity of the most-rostral pFRG in an in vitro brainstem-spinal cord preparation from neonatal rats. We detected strong pre-inspiratory neuron activity in the most rostral pFRG, suggesting that significant numbers of pre-inspiratory neurons are localized in the ventrolateral medulla near the rostral end of the medulla. We show that usage of calcium imaging would be very useful for analysis of neuronal activity over different time scales, and discuss the advantages and disadvantages of this method.
dc.formatapplication/pdf
dc.languageEnglish
dc.publisherSPRINGER JAPAN KK
dc.subjectNeurosciences not elsewhere classified; Clinical Health (Organs
dc.subjectDiseases and Abnormal Conditions) not elsewhere classified
dc.titleCalcium imaging of neuronal activity in the most rostral parafacial respiratory group of the newborn rat
dc.typeJournal Article
dc.identifier.doi10.1007/s12576-011-0179-2
melbourne.peerreviewPeer Reviewed
melbourne.affiliationThe University of Melbourne
melbourne.affiliation.departmentAnatomy And Neuroscience
melbourne.source.titleJournal of Physiological Sciences
melbourne.source.volume62
melbourne.source.issue1
melbourne.source.pages71-77
melbourne.publicationid195807
melbourne.elementsid387630
melbourne.contributor.authorDutschmann, Mathias
dc.identifier.eissn1880-6562
melbourne.fieldofresearch320999 Neurosciences not elsewhere classified
melbourne.seocode200199 Clinical health not elsewhere classified
melbourne.accessrightsThis item is currently not available from this repository


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