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dc.contributor.authorOkada, M
dc.contributor.authorWong, TY
dc.contributor.authorKawasaki, R
dc.contributor.authorBaharuddin, NB
dc.contributor.authorColville, D
dc.contributor.authorBuchanan, R
dc.contributor.authorSavige, J
dc.date.available2014-05-22T08:41:01Z
dc.date.issued2013-06-01
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000318646600010&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4d813f4571fa7d6246bdc0dfeca3a1c
dc.identifier.citationOkada, M., Wong, T. Y., Kawasaki, R., Baharuddin, N. B., Colville, D., Buchanan, R. & Savige, J. (2013). Retinal Venular Calibre is Increased in Patients with Autoimmune Rheumatic Disease: A Case-Control Study. CURRENT EYE RESEARCH, 38 (6), pp.685-690. https://doi.org/10.3109/02713683.2012.754046.
dc.identifier.issn0271-3683
dc.identifier.urihttp://hdl.handle.net/11343/33315
dc.descriptionC1 - Journal Articles Refereed
dc.description.abstractAIM: To examine retinal vessel calibre in autoimmune rheumatic disease. MATERIALS AND METHODS: Patients with autoimmune rheumatic disease were recruited from a Rheumatology clinic. Retinal vessel calibre was measured from fundus photographs, and summarised as the central retinal artery and vein equivalents (CRAE and CRVE) using a semi-automated computer-assisted method. RESULTS: The 124 patients studied had rheumatoid arthritis (n = 76, 61%), systemic lupus erythematosus (n = 17, 14%), psoriatic arthritis (n = 11, 9%) or another rheumatological disease (n = 20, 16%). Retinal venular calibre was increased in patients with autoimmune rheumatic disease (+11.6 µm, 95% Confidence interval [CI] 3.8 - 19.3, p = 0.01) compared with other hospital patients, after adjusting for baseline differences. This increase was also present in the subgroup with rheumatoid arthritis (p = 0.01). Patients with a rheumatic disease and elevated C-reactive protein (CRP) levels had wider retinal venules than those with a lower CRP (mean CRVE: 247.8 ± 28.0 versus 216.6 ± 25.3, p < 0.01), and than other hospital patients with increased CRP (mean CRVE: 247.8 ± 28.0 versus 216.4 ± 25.9, p < 0.01). CONCLUSIONS: Individuals with an autoimmune rheumatic disease have wider retinal venules than other hospital patients. This increase in calibre may be due to the underlying inflammatory activity.
dc.formatapplication/pdf
dc.languageEnglish
dc.publisherINFORMA HEALTHCARE
dc.subjectRheumatology and Arthritis; Ophthalmology; Cardiology (incl. Cardiovascular Diseases); Cardiovascular System and Diseases; Skeletal System and Disorders (incl. Arthritis)
dc.titleRetinal Venular Calibre is Increased in Patients with Autoimmune Rheumatic Disease: A Case-Control Study
dc.typeJournal Article
dc.identifier.doi10.3109/02713683.2012.754046
melbourne.peerreviewPeer Reviewed
melbourne.affiliationThe University of Melbourne
melbourne.affiliation.departmentMedicine - Royal Melbourne Hospital
melbourne.source.titleCURRENT EYE RESEARCH
melbourne.source.volume38
melbourne.source.issue6
melbourne.source.pages685-690
dc.research.codefor110322
dc.research.codefor111301
dc.research.codefor110201
dc.research.codeseo2008920103
dc.research.codeseo2008920116
melbourne.publicationid197867
melbourne.elementsid541397
melbourne.contributor.authorKawasaki, Ryo
melbourne.contributor.authorWong, Tien
melbourne.contributor.authorSavige, Judith
melbourne.contributor.authorCOLVILLE, DEBORAH JAN
melbourne.contributor.authorBuchanan, Russell
melbourne.contributor.authorOKADA, MALI
melbourne.contributor.authorBAHARUDDIN, NORASYIQIN
dc.identifier.eissn1460-2202
melbourne.accessrightsThis item is currently not available from this repository


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