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dc.contributor.authorWei, BPC
dc.contributor.authorShepherd, RK
dc.contributor.authorRobins-Browne, RM
dc.contributor.authorClark, GM
dc.contributor.authorO'Leary, SJ
dc.date.accessioned2014-05-22T08:47:42Z
dc.date.available2014-05-22T08:47:42Z
dc.date.issued2010-11
dc.identifierpii: S0194-5998(10)01984-4
dc.identifier.citationWei, B. P. C., Shepherd, R. K., Robins-Browne, R. M., Clark, G. M. & O'Leary, S. J. (2010). Pneumococcal meningitis post-cochlear implantation: preventative measures.. Otolaryngol Head Neck Surg, 143 (5 Suppl 3), pp.S9-14. https://doi.org/10.1016/j.otohns.2010.08.011.
dc.identifier.issn0194-5998
dc.identifier.urihttp://hdl.handle.net/11343/33351
dc.description© 2010 American Academy of Otolaryngology–Head and Neck Surgery Foundation. Published by Mosby, Inc. All rights reserved.
dc.description.abstractOBJECTIVE: Both clinical data and laboratory studies demonstrated the risk of pneumococcal meningitis post-cochlear implantation. This review examines strategies to prevent post-implant meningitis. DATA SOURCES: Medline/PubMed database; English articles after 1980. Search terms: cochlear implants, pneumococcus meningitis, streptococcus pneumonia, immunization, prevention. REVIEW METHODS: Narrative review. All articles relating to post-implant meningitis without any restriction in study designs were assessed and information extracted. RESULTS: The presence of inner ear trauma as a result of surgical technique or cochlear implant electrode array design was associated with a higher risk of post-implant meningitis. Laboratory data demonstrated the effectiveness of pneumococcal vaccination in preventing meningitis induced via the hematogenous route of infection. Fibrous sealing around the electrode array at the cochleostomy site, and the use of antibiotic-coated electrode array reduced the risk of meningitis induced via an otogenic route. CONCLUSION: The recent scientific data support the U.S. Food and Drug Administration recommendation of pneumococcal vaccination for the prevention of meningitis in implant recipients. Nontraumatic cochlear implant design, surgical technique, and an adequate fibrous seal around the cochleostomy site further reduce the risk of meningitis.
dc.languageeng
dc.publisherSAGE Publications
dc.relation.ispartofScientific publications, vol.14, 2004-2012
dc.subjectcochlear implants
dc.subjectmeningitis
dc.subjectStreptococcus pneumoniae
dc.subjectroutes of infection
dc.subjectthreshold model
dc.subjectprevention
dc.subjectimplant design and vaccination
dc.titlePneumococcal meningitis post-cochlear implantation: preventative measures.
dc.typeJournal Article
dc.identifier.doi10.1016/j.otohns.2010.08.011
melbourne.peerreviewPeer Reviewed
melbourne.affiliationThe University of Melbourne
melbourne.publication.statusPublished
melbourne.source.titleOtolaryngology
melbourne.source.volume143
melbourne.source.issue5 Suppl 3
melbourne.source.pagesS9-14
melbourne.elementsid329129
melbourne.contributor.authorWei, Benjamin
melbourne.contributor.authorShepherd, Robert
melbourne.contributor.authorRobins-Browne, Roy
melbourne.contributor.authorClark, Graeme
melbourne.contributor.authorO'Leary, Stephen
dc.identifier.eissn1097-6817
melbourne.accessrightsOpen Access


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