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dc.contributor.authorWong, Tien Yinen_US
dc.contributor.authorLarsen, Emily K. Marinoen_US
dc.contributor.authorKlein, Ronalden_US
dc.contributor.authorMITCHELL, PAULen_US
dc.contributor.authorCouper, David J.en_US
dc.contributor.authorKlein, Barbara E. K.en_US
dc.contributor.authorHubbard, Larry D.en_US
dc.contributor.authorSiscovick, David S.en_US
dc.contributor.authorSharrett, A. Richeyen_US
dc.identifier.citationWong, T. Y., Larsen, E. K. M., Klein, R., Mitchell, P., Couper, D. J., Klein, B. E. K., et al. (2005). Cardiovascular risk factors for retinal vein occlusion and arteriolar emboli: the atherosclerosis risk in communities & cardiovascular health studies. Ophthalmology: journal of the American Academy of Ophthalmology, 112(4), 540-547.en_US
dc.description.abstractObjective: To examine the associations of retinal vein occlusion and arteriolar emboli with cardiovascular disease. Design: Population-based cross-sectional study. Participants: Pooled from the Atherosclerosis Risk in Communities Study (n = 12 642; mean age, 60 years) and the Cardiovascular Health Study (n = 2824; mean age, 79 years). Methods: Retinal vein occlusion and arteriolar emboli were identified from a single nonmydriatic retinal photograph using a standardized protocol. Photographs were also graded for arteriovenous nicking and focal arteriolar narrowing. All participants had a comprehensive systemic evaluation, including standardized carotid ultrasonography. Main Outcome Measures: Retinal vein occlusion and arteriolar emboli. Results: Prevalences of retinal vein occlusion and arteriolar emboli were 0.3% (n = 39 cases) and 0.2% (n = 34 cases), respectively. After adjusting for age, retinal vein occlusion was associated with hypertension (odds ratio OR, 2.96; 95% confidence interval CI, 1.43­6.14), systolic blood pressure (BP) (OR, 4.12; 95% CI, 1.40­12.16; highest quartile vs. lowest), diastolic BP (OR, 2.64; 95% CI, 1.07­6.46; highest quartile vs. lowest), carotid artery plaque (OR, 5.62; 95% CI, 2.60­12.16), body mass index (OR, 3.88; 95% CI, 1.23­12.18; highest quartile vs. lowest), plasma fibrinogen (OR, 3.29; 95% CI, 1.08­10.02; highest quartile vs. lowest), arteriovenous nicking (OR, 4.09; 95% CI, 2.00­8.36), and focal arteriolar narrowing (OR, 5.17; 95% CI, 2.59­10.29). After adjusting for age, retinal arteriolar emboli were associated with hypertension (OR, 3.14; 95% CI, 1.44­6.84), systolic BP (OR, 3.46; 95% CI, 1.13­10.65; highest quartile vs. lowest), prevalent coronary heart disease (OR, 2.33! ; 95% CI, 1.01­5.42), carotid artery plaque (OR, 4.62; 95% CI, 1.85­11.57), plasma lipoprotein (a) (OR, 3.6 []en_US
dc.subjectCentre for Eye Research Australiaen_US
dc.subjecteye researchen_US
dc.subjectvisual healthen_US
dc.titleCardiovascular risk factors for retinal vein occlusion and arteriolar emboli: the atherosclerosis risk in communities & cardiovascular health studiesen_US
dc.typeJournal (Paginated)en_US
melbourne.peerreviewPeer Revieweden_US
melbourne.affiliation.departmentMedicine, Dentistry and Health Sciences: Centre for Eye Research Australiaen_US
melbourne.affiliation.departmentSchool of Medicine: Ophthalmologyen_US
melbourne.source.titleOphthalmology: journal of the American Academy of Ophthalmologyen_US
melbourne.contributor.authorWong, Tien
melbourne.accessrightsThis item is currently not available from this repository

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