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Coexistence of Reward and Unsupervised Learning During the Operant Conditioning of Neural Firing Rates
(PUBLIC LIBRARY SCIENCE, 2014-01-27)A fundamental goal of neuroscience is to understand how cognitive processes, such as operant conditioning, are performed by the brain. Typical and well studied examples of operant conditioning, in which the firing rates ... -
Hypothermia protects human neurons
(SAGE PUBLICATIONS LTD, 2014-07-01)BACKGROUND AND AIMS: Hypothermia provides neuroprotection after cardiac arrest, hypoxic-ischemic encephalopathy, and in animal models of ischemic stroke. However, as drug development for stroke has been beset by translational ... -
Integration of Steady-State and Temporal Gene Expression Data for the Inference of Gene Regulatory Networks
(PUBLIC LIBRARY SCIENCE, 2013-08-14)We develop a new regression algorithm, cMIKANA, for inference of gene regulatory networks from combinations of steady-state and time-series gene expression data. Using simulated gene expression datasets to assess the ...