Biomedical Engineering - Research Publications
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Colour-based computer image processing approach to melanoma diagnosis
(2017)
Melanoma is one of the most prevalent skin cancers in the world. The incidence and mortality rates of melanoma in Australian populations have been sharply increasing over the last decades. For instance, it is represented ...
Generation of Adrenal Chromaffin-like Cells from Human Pluripotent Stem Cells
(CELL PRESS, 2018-01-09)
Adrenomedullary chromaffin cells are catecholamine (CA)-producing cells originating from trunk neural crest (NC) via sympathoadrenal progenitors (SAPs). We generated NC and SAPs from human embryonic stem cells (ESCs) and ...
2-DIMENSIONAL DIFFUSION OF AMPHIPHILES IN PHOSPHOLIPID MONOLAYERS AT THE AIR-WATER-INTERFACE
(CELL PRESS, 1993-12-01)
Steady-state and time-resolved fluorescence spectroscopy has been used to examine lateral diffusion in dipalmitoyl-L-alpha-phosphatidylcholine (DPPC) and dimyristoyl-L-alpha-phosphatidylcholine (DMPC) monolayers at the ...
Automated framework to reconstruct 3D model of cardiac Z-disk: an image processing approach
(IEEE, 2018-01-01)
The Z-disk or Z-line is located at the lateral borders of sarcomere, the fundamental unit of striated muscle. They provide mechanical stability and can boost contractility of cardiac myocytes. In this paper, we propose to ...
Signal quality of simultaneously recorded endovascular, subdural and epidural signals are comparable
(NATURE PUBLISHING GROUP, 2018-05-30)
Recent work has demonstrated the feasibility of minimally-invasive implantation of electrodes into a cortical blood vessel. However, the effect of the dura and blood vessel on recording signal quality is not understood and ...
Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells
(NATURE PUBLISHING GROUP, 2018-01-12)
The dorsal root ganglia (DRG) consist of a multitude of sensory neuronal subtypes that function to relay sensory stimuli, including temperature, pressure, pain and position to the central nervous system. Our knowledge of ...
Trophic effects of adipose-tissue-derived and bone-marrow-derived mesenchymal stem cells enhance cartilage generation by chondrocytes in co-culture.
(2018)
AIMS: Combining mesenchymal stem cells (MSCs) and chondrocytes has great potential for cell-based cartilage repair. However, there is much debate regarding the mechanisms behind this concept. We aimed to clarify the ...
Decellularized extracellular matrices produced from immortal cell lines derived from different parts of the placenta support primary mesenchymal stem cell expansion
(PUBLIC LIBRARY SCIENCE, 2017-02-02)
Mesenchymal stem/stromal cells (MSCs) exhibit undesired phenotypic changes during ex vivo expansion, limiting production of the large quantities of high quality primary MSCs needed for both basic research and cell therapies. ...
Friedreich's ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency
(IMPACT JOURNALS LLC, 2017-05-01)
We sought to identify the impacts of Friedreich's ataxia (FRDA) on cardiomyocytes. FRDA is an autosomal recessive degenerative condition with neuronal and non-neuronal manifestations, the latter including progressive ...
The Convergence of Cochlear Implantation with Induced Pluripotent Stem Cell Therapy
(HUMANA PRESS INC, 2012-09-01)
According to 2010 estimates from The National Institute on Deafness and other Communication Disorders, approximately 17% (36 million) American adults have reported some degree of hearing loss. Currently, the only clinical ...
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