Nanoengineering has recently emerged as a promising technology for the understanding, treatment, and diagnosis of disease. One of its most compelling potential uses is in the design of particles with controlled interactions ...

One of the main concerns of visual neuroscience is to understand how information is processed by the neural circuits in the visual system. Since the historic experiments of Hubel and Wiesel, many more aspects of visual ...

The concentration of calcium ions (Ca2+) within a cell is important for governing many different processes across a range of cell types. In heart muscle cells, proper calcium handling is critical for maintaining the ...

Magnetic resonance imaging (MRI) is a powerful imaging modality, widely used in routine clinical practice and as an investigational tool in basic science. The contrast in MRI is related to both the underlying tissue ...

Epilepsy affects around 50 million people worldwide. Brain injuries and lesions, such as traumatic brain injury, central nervous system infection and stroke, are associated with higher risk of developing epilepsy. It is ...

Evaluation of the muscle forces generated during shoulder motion is critical in our understanding of shoulder disease and injury prevention, prosthesis design and rehabilitation. Since non-invasive muscle force measurement ...

Retinal prostheses are a promising treatment for blindness caused by photoreceptor degeneration. Electrodes implanted in the retina deliver electrical stimuli in the form of current pulses that activate surviving neurons ...

This thesis is concerned with the development of template-based computational model of sound recognition called Biotemp. Biotemp is developed using neurobiologically plausible processing stages and based on the observation ...

This research develops a framework for modeling the electrical properties of neu- ral tissue based on its cellular constituents. This has application to modeling of electrical stimulation of neural tissue, including for ...

The processing of motion information in the brain initiates in the primary area of visual cortex (V1). V1 neurons transmit initial estimates of the motion of stimuli to neurons in higher areas of the cortex. However, V1 ...