• Oestrogen Activates the MAP3K1 Cascade and beta-Catenin to Promote Granulosa-like Cell Fate in a Human Testis-Derived Cell Line 

  Stewart, MK; Bernard, P; Ang, C-S; Mattiske, DM; Pask, AJ (MDPI, 2021-09-01)

  Sex determination triggers the differentiation of the bi-potential gonad into either an ovary or testis. In non-mammalian vertebrates, the presence or absence of oestrogen dictates gonad differentiation, while in mammals, ...

• Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. 

  Xie, SC; Metcalfe, RD; Mizutani, H; Puhalovich, T; Hanssen, E; Morton, CJ; Du, Y; Dogovski, C; Huang, S-C; Ciavarri, J; ... (Proceedings of the National Academy of Sciences, 2021-09-28)

  The Plasmodium falciparum proteasome is a potential antimalarial drug target. We have identified a series of amino-amide boronates that are potent and specific inhibitors of the P. falciparum 20S proteasome (Pf20S) β5 ...

• Occupational Allergic Sensitization Among Workers Processing King Crab (Paralithodes camtschaticus) and Edible Crab (Cancer pagurus) in Norway and Identification of Novel Putative Allergenic Proteins 

  Thomassen, MR; Kamath, SD; Bang, BE; Nugraha, R; Nie, S; Williamson, NA; Lopata, AL; Aasmoe, L (Frontiers Media SA, 2021-08-23)

  Introduction: Asthma and allergy occur frequently among seafood processing workers, with the highest prevalence seen in the crustacean processing industry. In this study we established for the first time the prevalence of ...

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