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Literature consistency of bioinformatics sequence databases is effective for assessing record quality
(OXFORD UNIV PRESS, 2017-03-18)Bioinformatics sequence databases such as Genbank or UniProt contain hundreds of millions of records of genomic data. These records are derived from direct submissions from individual laboratories, as well as from bulk ... -
Interactions within the MHC contribute to the genetic architecture of celiac disease
(PUBLIC LIBRARY SCIENCE, 2017-03-10)Interaction analysis of GWAS can detect signal that would be ignored by single variant analysis, yet few robust interactions in humans have been detected. Recent work has highlighted interactions in the MHC region between ... -
Duplicates, redundancies and inconsistencies in the primary nucleotide databases: a descriptive study
(OXFORD UNIV PRESS, 2017-01-10)GenBank, the EMBL European Nucleotide Archive and the DNA DataBank of Japan, known collectively as the International Nucleotide Sequence Database Collaboration or INSDC, are the three most significant nucleotide sequence ...